SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ubd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ubd MONOCLONAL ANTIBODY
H CHAIN
(Homo
sapiens) 		3 / 3 ARG C 112
VAL C  37
TRP C  47
 None
 1.18A 1qw6A-4ubdC:
undetectable		 1qw6A-4ubdC:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ubd MONOCLONAL ANTIBODY
H CHAIN
(Homo
sapiens) 		3 / 3 ARG C 112
VAL C  37
TRP C  47
 None
 1.23A 1qwcA-4ubdC:
undetectable		 1qwcA-4ubdC:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ubd MONOCLONAL ANTIBODY
H CHAIN
(Homo
sapiens) 		3 / 3 ARG C 112
VAL C  37
TRP C  47
 None
 1.16A 1vagA-4ubdC:
undetectable		 1vagA-4ubdC:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4ubd MONOCLONAL ANTIBODY
H CHAIN
(Homo
sapiens) 		3 / 3 ARG C 112
VAL C  37
TRP C  47
 None
 1.24A 1zviA-4ubdC:
undetectable		 1zviA-4ubdC:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 4ubd MONOCLONAL ANTIBODY
H CHAIN
(Homo
sapiens) 		3 / 3 ARG C 104
ASP C  99
ASP C  59
 None
 0.85A 2ejtA-4ubdC:
undetectable		 2ejtA-4ubdC:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 4ubd MONOCLONAL ANTIBODY
H CHAIN
(Homo
sapiens) 		4 / 5 SER C  85
ARG C  87
PRO C  88
VAL C 124
 None
 1.12A 3sufC-4ubdC:
undetectable		 3sufC-4ubdC:
24.59