SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ud4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
5 / 8 LYS A 144
LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.99A 1v54C-4ud4A:
undetectable
1v54J-4ud4A:
undetectable
1v54C-4ud4A:
19.95
1v54J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
5 / 7 LYS A 144
LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.99A 1v55C-4ud4A:
undetectable
1v55J-4ud4A:
undetectable
1v55C-4ud4A:
19.95
1v55J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
5 / 8 LYS A 144
LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.98A 2dyrC-4ud4A:
undetectable
2dyrJ-4ud4A:
undetectable
2dyrC-4ud4A:
19.95
2dyrJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
5 / 8 LYS A 144
LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
1.00A 2dyrP-4ud4A:
undetectable
2dyrW-4ud4A:
undetectable
2dyrP-4ud4A:
19.95
2dyrW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LYS A 144
LEU A 145
GLN A 158
LEU A 125
None
0.95A 2dysP-4ud4A:
undetectable
2dysW-4ud4A:
undetectable
2dysP-4ud4A:
19.95
2dysW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
5 / 7 LYS A 144
LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.99A 2eijC-4ud4A:
undetectable
2eijJ-4ud4A:
undetectable
2eijC-4ud4A:
19.95
2eijJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.94A 2eikC-4ud4A:
undetectable
2eikJ-4ud4A:
undetectable
2eikC-4ud4A:
19.95
2eikJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
5 / 8 LYS A 144
LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.94A 2eilC-4ud4A:
undetectable
2eilJ-4ud4A:
undetectable
2eilC-4ud4A:
19.95
2eilJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
5 / 7 LYS A 144
LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.90A 2eimC-4ud4A:
undetectable
2eimJ-4ud4A:
undetectable
2eimC-4ud4A:
19.95
2eimJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.93A 2einC-4ud4A:
undetectable
2einJ-4ud4A:
undetectable
2einC-4ud4A:
19.95
2einJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LYS A 144
LEU A 145
GLN A 158
LEU A 125
None
0.95A 2einC-4ud4A:
undetectable
2einJ-4ud4A:
undetectable
2einC-4ud4A:
19.95
2einJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.03A 2y69C-4ud4A:
undetectable
2y69J-4ud4A:
undetectable
2y69C-4ud4A:
19.95
2y69J-4ud4A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.11A 2y69P-4ud4A:
undetectable
2y69W-4ud4A:
undetectable
2y69P-4ud4A:
19.95
2y69W-4ud4A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
5 / 12 ILE A 328
LEU A 326
ILE A 350
VAL A 192
VAL A 189
None
1.04A 2ygnA-4ud4A:
undetectable
2ygnA-4ud4A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
3 / 3 SER A 210
GLU A 333
ASP A 246
None
0.78A 2zulA-4ud4A:
undetectable
2zulA-4ud4A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
1.00A 2zxwP-4ud4A:
undetectable
2zxwW-4ud4A:
undetectable
2zxwP-4ud4A:
19.95
2zxwW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.03A 3abmC-4ud4A:
undetectable
3abmJ-4ud4A:
undetectable
3abmC-4ud4A:
19.95
3abmJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.04A 3abmP-4ud4A:
undetectable
3abmW-4ud4A:
undetectable
3abmP-4ud4A:
19.95
3abmW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
1.01A 3ag1C-4ud4A:
undetectable
3ag1J-4ud4A:
undetectable
3ag1C-4ud4A:
19.95
3ag1J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.09A 3ag3C-4ud4A:
undetectable
3ag3J-4ud4A:
undetectable
3ag3C-4ud4A:
19.95
3ag3J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 8 LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.91A 3ag4C-4ud4A:
undetectable
3ag4J-4ud4A:
undetectable
3ag4C-4ud4A:
19.95
3ag4J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.96A 3ag4P-4ud4A:
undetectable
3ag4W-4ud4A:
undetectable
3ag4P-4ud4A:
19.95
3ag4W-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.93A 3asnC-4ud4A:
undetectable
3asnJ-4ud4A:
undetectable
3asnC-4ud4A:
19.95
3asnJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LYS A 144
LEU A 145
LEU A 125
PHE A 121
None
0.93A 3asnP-4ud4A:
undetectable
3asnW-4ud4A:
undetectable
3asnP-4ud4A:
19.95
3asnW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
3 / 3 SER A 210
GLU A 333
ASP A 246
None
0.75A 3dmhA-4ud4A:
undetectable
3dmhA-4ud4A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 8 ASP A 253
HIS A 170
LEU A 181
LEU A 234
None
0.99A 3lm8B-4ud4A:
undetectable
3lm8D-4ud4A:
undetectable
3lm8B-4ud4A:
20.27
3lm8D-4ud4A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 4 VAL A 290
PHE A 278
PHE A 276
VAL A 192
None
1.39A 3rv5C-4ud4A:
undetectable
3rv5D-4ud4A:
undetectable
3rv5C-4ud4A:
13.70
3rv5D-4ud4A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 LEU A 145
PHE A 130
LEU A 125
PHE A 121
None
1.02A 3wg7C-4ud4A:
undetectable
3wg7J-4ud4A:
undetectable
3wg7C-4ud4A:
19.95
3wg7J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 145
GLN A 158
LEU A 125
PHE A 121
None
0.96A 3x2qC-4ud4A:
undetectable
3x2qJ-4ud4A:
undetectable
3x2qC-4ud4A:
19.95
3x2qJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 PHE A 275
PHE A 276
ALA A 196
LEU A 373
None
0.92A 4ejgC-4ud4A:
undetectable
4ejgC-4ud4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 CYH A  48
LEU A 272
HIS A 194
LEU A 191
None
1.18A 5hpuC-4ud4A:
undetectable
5hpuD-4ud4A:
undetectable
5hpuC-4ud4A:
6.83
5hpuD-4ud4A:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 LYS A 144
LEU A 145
LEU A 125
PHE A 121
None
0.80A 5w97C-4ud4A:
undetectable
5w97J-4ud4A:
undetectable
5w97C-4ud4A:
19.95
5w97J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.09A 5wauC-4ud4A:
undetectable
5wauJ-4ud4A:
undetectable
5wauC-4ud4A:
19.95
5wauJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.08A 5wauc-4ud4A:
undetectable
5wauj-4ud4A:
undetectable
5wauc-4ud4A:
19.95
5wauj-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 LEU A 145
PHE A 130
LEU A 125
PHE A 121
None
1.02A 5x19C-4ud4A:
undetectable
5x19J-4ud4A:
undetectable
5x19C-4ud4A:
19.95
5x19J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 7 LYS A 144
LEU A 145
LEU A 125
PHE A 121
None
0.75A 5x1fP-4ud4A:
undetectable
5x1fW-4ud4A:
undetectable
5x1fP-4ud4A:
19.95
5x1fW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.07A 5xdqC-4ud4A:
undetectable
5xdqJ-4ud4A:
undetectable
5xdqC-4ud4A:
19.95
5xdqJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.07A 5xdqP-4ud4A:
undetectable
5xdqW-4ud4A:
undetectable
5xdqP-4ud4A:
19.95
5xdqW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.10A 5z84P-4ud4A:
undetectable
5z84W-4ud4A:
undetectable
5z84P-4ud4A:
19.95
5z84W-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.07A 5z86C-4ud4A:
undetectable
5z86J-4ud4A:
undetectable
5z86C-4ud4A:
19.95
5z86J-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.07A 5z86P-4ud4A:
undetectable
5z86W-4ud4A:
undetectable
5z86P-4ud4A:
19.95
5z86W-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.06A 5zcoP-4ud4A:
undetectable
5zcoW-4ud4A:
undetectable
5zcoP-4ud4A:
19.95
5zcoW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.06A 5zcpC-4ud4A:
undetectable
5zcpJ-4ud4A:
undetectable
5zcpC-4ud4A:
19.95
5zcpJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 PHE A 153
PHE A 130
LEU A 125
PHE A 121
None
1.11A 5zcpP-4ud4A:
undetectable
5zcpW-4ud4A:
undetectable
5zcpP-4ud4A:
19.95
5zcpW-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
3 / 3 ARG A 184
LEU A 271
PHE A 275
None
0.73A 6nknP-4ud4A:
undetectable
6nknP-4ud4A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 6 LYS A 144
GLN A 158
LEU A 125
PHE A 121
None
1.04A 6nmpC-4ud4A:
undetectable
6nmpJ-4ud4A:
undetectable
6nmpC-4ud4A:
19.95
6nmpJ-4ud4A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4ud4 POLY(A) RNA
POLYMERASE PROTEIN
CID1

(Schizosaccharomy
ces
pombe)
4 / 5 ARG A 184
LEU A 271
PHE A 275
PHE A 231
None
1.41A 6nmpP-4ud4A:
undetectable
6nmpW-4ud4A:
undetectable
6nmpP-4ud4A:
19.95
6nmpW-4ud4A:
10.26