SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4udj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 4udj UHGB_MP
(uncultured
organism) 		5 / 12 GLY A 152
ILE A 180
ALA A 215
SER A 183
TYR A 182
 None
 0.98A 1ri4A-4udjA:
undetectable		 1ri4A-4udjA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 4udj UHGB_MP
(uncultured
organism) 		5 / 12 ARG A  14
SER A 246
LEU A 227
PRO A 217
ILE A 229
 None
 1.45A 1ynnC-4udjA:
1.6		 1ynnC-4udjA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 4udj UHGB_MP
(uncultured
organism) 		4 / 6 PHE A 145
TYR A 182
ARG A 162
GLY A 192
 None
 1.42A 2i30A-4udjA:
undetectable		 2i30A-4udjA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 4udj UHGB_MP
(uncultured
organism) 		4 / 5 LEU A 249
LEU A 228
LEU A 265
MET A 198
 None
 1.09A 2oaxF-4udjA:
undetectable		 2oaxF-4udjA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 4udj UHGB_MP
(uncultured
organism) 		3 / 3 SER A 261
ARG A 260
GLN A 209
 None
 0.93A 2xnrA-4udjA:
undetectable		 2xnrA-4udjA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4udj UHGB_MP
(uncultured
organism) 		5 / 12 TYR A 300
ASN A  28
PRO A  29
THR A 307
SER A  41
 None
None
PGE  A 608 (-3.8A)
None
K  A 606 (-2.6A)
 1.27A 3g4lA-4udjA:
undetectable		 3g4lA-4udjA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 4udj UHGB_MP
(uncultured
organism) 		4 / 7 ARG A 106
ILE A 218
THR A 132
THR A 307
 None
 1.27A 3nxuA-4udjA:
undetectable		 3nxuA-4udjA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 4udj UHGB_MP
(uncultured
organism) 		5 / 12 ILE A 314
GLY A 225
VAL A 197
PRO A 219
LEU A 166
 None
None
K  A 333 (-4.6A)
None
None
 0.99A 3v8vA-4udjA:
undetectable		 3v8vA-4udjA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 4udj UHGB_MP
(uncultured
organism) 		4 / 6 MET A  67
ASP A  61
ARG A  59
HIS A  70
 None
None
BMA  A 329 (-4.0A)
None
 1.49A 4cevA-4udjA:
undetectable
4cevC-4udjA:
undetectable		 4cevA-4udjA:
22.28
4cevC-4udjA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 4udj UHGB_MP
(uncultured
organism) 		4 / 8 ARG A 157
THR A 222
PRO A 223
ILE A 314
 None
 0.91A 6a4iA-4udjA:
undetectable		 6a4iA-4udjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 4udj UHGB_MP
(uncultured
organism) 		4 / 8 THR A 222
PRO A 223
ILE A 318
PRO A 315
 None
 0.94A 6a4iA-4udjA:
undetectable		 6a4iA-4udjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4udj UHGB_MP
(uncultured
organism) 		4 / 6 GLY A 102
VAL A 107
PHE A  58
PHE A 135
 None
 1.01A 6h7lA-4udjA:
undetectable		 6h7lA-4udjA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4udj UHGB_MP
(uncultured
organism) 		4 / 6 GLY A 102
VAL A 107
PHE A  58
PHE A 135
 None
 1.02A 6h7lB-4udjA:
undetectable		 6h7lB-4udjA:
14.39