SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4udn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 12 ALA A 238
THR A 273
ILE A 270
LEU A 244
THR A 236
 None
 1.16A 1dhfA-4udnA:
undetectable		 1dhfA-4udnA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 12 ALA A 238
THR A 273
ILE A 270
LEU A 244
THR A 236
 None
 1.21A 1dhfB-4udnA:
undetectable		 1dhfB-4udnA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 9 LEU A  58
SER A   9
THR A  29
VAL A  28
ALA A  54
 None
None
SO4  A1276 (-4.0A)
None
None
 1.29A 1fo4A-4udnA:
0.8		 1fo4A-4udnA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 6 LEU A  64
PHE A  11
TYR A 259
VAL A  32
 None
 1.24A 1ibgH-4udnA:
undetectable		 1ibgH-4udnA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 11 ILE A  88
LEU A  64
PRO A 103
VAL A  32
TYR A  68
 None
 1.39A 1mrlA-4udnA:
undetectable
1mrlB-4udnA:
undetectable		 1mrlA-4udnA:
20.57
1mrlB-4udnA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 12 ILE A  88
LEU A  64
PRO A 103
VAL A  32
TYR A  68
 None
 1.38A 1mrlB-4udnA:
undetectable
1mrlC-4udnA:
undetectable		 1mrlB-4udnA:
20.57
1mrlC-4udnA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 5 ALA A 233
TYR A 240
ILE A 218
ASP A 226
 None
 1.16A 1upfA-4udnA:
undetectable		 1upfA-4udnA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 5 ALA A 233
TYR A 240
ILE A 218
ASP A 226
 None
 0.97A 1upfC-4udnA:
undetectable		 1upfC-4udnA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 11 VAL A   7
ILE A  14
GLY A  15
ILE A  21
LEU A 125
 None
 0.89A 1z11A-4udnA:
undetectable		 1z11A-4udnA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 11 VAL A   7
ILE A  14
GLY A  15
ILE A  21
LEU A 125
 None
 0.92A 1z11B-4udnA:
undetectable		 1z11B-4udnA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 10 VAL A   7
ILE A  14
GLY A  15
ILE A  21
LEU A 125
 None
 0.88A 1z11C-4udnA:
undetectable		 1z11C-4udnA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 10 VAL A   7
ILE A  14
GLY A  15
ILE A  21
LEU A 125
 None
 0.90A 1z11D-4udnA:
undetectable		 1z11D-4udnA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 6 ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 0.97A 2dcfA-4udnA:
undetectable		 2dcfA-4udnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 12 MET A 115
ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 1.15A 2dcfA-4udnA:
undetectable		 2dcfA-4udnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 10 ALA A 238
THR A 273
ILE A 270
LEU A 244
THR A 236
 None
 1.22A 2w3aB-4udnA:
undetectable		 2w3aB-4udnA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 7 ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 0.94A 2zm7A-4udnA:
undetectable		 2zm7A-4udnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 10 MET A 115
ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 1.13A 2zm7A-4udnA:
undetectable		 2zm7A-4udnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 8 ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 0.94A 2zm8A-4udnA:
undetectable		 2zm8A-4udnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA512_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 10 MET A 115
ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 1.12A 2zm8A-4udnA:
undetectable		 2zm8A-4udnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 8 MET A 115
ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 1.12A 2zm9A-4udnA:
undetectable		 2zm9A-4udnA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 8 ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 0.96A 2zmaA-4udnA:
undetectable		 2zmaA-4udnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 11 MET A 115
ALA A 114
TYR A 143
TYR A 259
ILE A 118
 None
 1.13A 2zmaA-4udnA:
undetectable		 2zmaA-4udnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 8 TYR A 177
VAL A 176
VAL A 246
GLY A 173
 None
 0.92A 3hjoA-4udnA:
undetectable		 3hjoA-4udnA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 7 TYR A 177
VAL A 176
VAL A 246
GLY A 173
 None
 0.95A 3kmoB-4udnA:
undetectable		 3kmoB-4udnA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 9 LEU A  58
VAL A  28
ILE A  21
ALA A  22
ALA A 124
 None
 0.98A 3mdvA-4udnA:
undetectable		 3mdvA-4udnA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 12 LEU A  58
VAL A  28
ILE A  21
ALA A  22
ALA A 124
 None
 0.96A 3mdvB-4udnA:
undetectable		 3mdvB-4udnA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 9 LEU A  58
SER A   9
THR A  29
VAL A  28
ALA A  54
 None
None
SO4  A1276 (-4.0A)
None
None
 1.29A 3unaA-4udnA:
undetectable		 3unaA-4udnA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 9 LEU A  58
SER A   9
THR A  29
VAL A  28
ALA A  54
 None
None
SO4  A1276 (-4.0A)
None
None
 1.28A 3unaB-4udnA:
0.7		 3unaB-4udnA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 9 LEU A  58
SER A   9
THR A  29
VAL A  28
ALA A  54
 None
None
SO4  A1276 (-4.0A)
None
None
 1.27A 3uncA-4udnA:
undetectable		 3uncA-4udnA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 9 LEU A  58
SER A   9
THR A  29
VAL A  28
ALA A  54
 None
None
SO4  A1276 (-4.0A)
None
None
 1.28A 3uncB-4udnA:
undetectable		 3uncB-4udnA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 12 VAL A 169
ILE A 218
GLU A  95
HIS A 205
VAL A 232
 None
None
GOL  A1282 (-3.1A)
GOL  A1281 (-4.6A)
None
 1.33A 4a97B-4udnA:
undetectable
4a97C-4udnA:
undetectable		 4a97B-4udnA:
22.77
4a97C-4udnA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 8 LEU A  58
VAL A   7
VAL A  28
GLN A  19
 None
 0.92A 4em2A-4udnA:
undetectable		 4em2A-4udnA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 12 LEU A 263
LEU A 244
LEU A 175
LEU A 178
ILE A  13
 None
 1.01A 4odrA-4udnA:
undetectable
4odrB-4udnA:
undetectable		 4odrA-4udnA:
19.07
4odrB-4udnA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 11 LEU A 263
LEU A 244
LEU A 175
LEU A 178
ILE A  13
 None
 1.08A 4odrA-4udnA:
undetectable
4odrB-4udnA:
undetectable		 4odrA-4udnA:
19.07
4odrB-4udnA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		5 / 9 ALA A 206
ASN A 104
VAL A  93
GLY A 173
SER A 199
 None
 1.14A 4r20B-4udnA:
undetectable		 4r20B-4udnA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4udn PERIPLASMIC SOLUTE
BINDING PROTEIN
(Candidatus
Liberibacter
asiaticus) 		4 / 5 ALA A 140
TYR A 143
GLY A 173
LEU A 262
 None
 0.99A 5eslA-4udnA:
undetectable		 5eslA-4udnA:
20.54