SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ueg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		3 / 3 LEU A 145
HIS A  90
ILE A  72
 None
 0.71A 1s9pB-4uegA:
undetectable		 1s9pB-4uegA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		5 / 12 TYR A 264
VAL A  45
ALA A 105
CYH A  18
TYR A 256
 None
 1.31A 2g70A-4uegA:
undetectable		 2g70A-4uegA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		5 / 12 LEU A  94
VAL A  38
HIS A 148
LEU A 152
TYR A  71
 None
 1.15A 2prgB-4uegA:
undetectable		 2prgB-4uegA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		4 / 7 ALA A  12
ALA A 105
VAL A  45
ILE A  52
 None
 0.59A 3a2qA-4uegA:
undetectable		 3a2qA-4uegA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		4 / 4 ARG A 119
GLN A 142
PHE A 141
LEU A 185
 None
 1.40A 3abkC-4uegA:
undetectable		 3abkC-4uegA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		4 / 5 ARG A 119
GLN A 142
PHE A 141
LEU A 185
 None
 1.43A 3ablC-4uegA:
undetectable
3ablJ-4uegA:
undetectable		 3ablC-4uegA:
21.54
3ablJ-4uegA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		5 / 12 LEU A  94
LEU A  11
HIS A 148
LEU A 152
TYR A  71
 None
 1.29A 3adsA-4uegA:
undetectable		 3adsA-4uegA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		5 / 12 THR A  34
VAL A 101
LEU A 185
SER A  27
VAL A 138
 None
 1.36A 3frqA-4uegA:
undetectable		 3frqA-4uegA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		4 / 4 LEU A  94
LEU A  11
GLN A   6
GLU A 121
 None
 1.27A 4i41A-4uegA:
undetectable		 4i41A-4uegA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		5 / 12 LEU A  94
VAL A   9
HIS A 148
LEU A 152
TYR A  71
 None
 1.05A 4o8fB-4uegA:
undetectable		 4o8fB-4uegA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		5 / 12 LEU A  94
VAL A  38
HIS A 148
LEU A 152
TYR A  71
 None
 1.10A 4o8fB-4uegA:
undetectable		 4o8fB-4uegA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		5 / 12 SER A  27
LEU A  24
GLY A  25
VAL A  56
LEU A 103
 None
 1.38A 5jo9A-4uegA:
3.0		 5jo9A-4uegA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4ueg GLYCOGENIN-2
(Homo
sapiens) 		4 / 6 ARG A 119
GLN A 142
PHE A 141
LEU A 185
 None
 1.31A 6nmpC-4uegA:
undetectable
6nmpJ-4uegA:
undetectable		 6nmpC-4uegA:
21.54
6nmpJ-4uegA:
12.37