SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4uei STEROL CARRIER
PROTEIN
2/3-OXOACYL-COA
THIOLASE
(Helicoverpa
armigera) 		3 / 3 ASN A  80
ILE A  68
MET A  29
 None
 0.58A 2h42C-4ueiA:
undetectable		 2h42C-4ueiA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4uei STEROL CARRIER
PROTEIN
2/3-OXOACYL-COA
THIOLASE
(Helicoverpa
armigera) 		4 / 8 ARG A  48
GLU A  37
ILE A  44
ASN A  69
 None
 0.83A 4d33A-4ueiA:
undetectable		 4d33A-4ueiA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4uei STEROL CARRIER
PROTEIN
2/3-OXOACYL-COA
THIOLASE
(Helicoverpa
armigera) 		4 / 7 ARG A  48
GLU A  37
ILE A  44
ASN A  69
 None
 0.92A 4d33B-4ueiA:
undetectable		 4d33B-4ueiA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4uei STEROL CARRIER
PROTEIN
2/3-OXOACYL-COA
THIOLASE
(Helicoverpa
armigera) 		4 / 8 ARG A  48
GLU A  37
ILE A  44
ASN A  69
 None
 0.99A 4d39A-4ueiA:
undetectable		 4d39A-4ueiA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4uei STEROL CARRIER
PROTEIN
2/3-OXOACYL-COA
THIOLASE
(Helicoverpa
armigera) 		4 / 7 ARG A  48
GLU A  37
ILE A  44
ASN A  69
 None
 1.00A 4d39B-4ueiA:
undetectable		 4d39B-4ueiA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4uei STEROL CARRIER
PROTEIN
2/3-OXOACYL-COA
THIOLASE
(Helicoverpa
armigera) 		3 / 3 ASP A  95
ASN A 105
PHE A 111
 None
 0.73A 5dsgB-4ueiA:
undetectable		 5dsgB-4ueiA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 4uei STEROL CARRIER
PROTEIN
2/3-OXOACYL-COA
THIOLASE
(Helicoverpa
armigera) 		5 / 12 GLU A  33
GLY A  75
GLU A  45
ALA A  70
TYR A  51
 None
 1.16A 5n5dA-4ueiA:
undetectable		 5n5dA-4ueiA:
20.19