SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		3 / 3 THR A 446
PRO A 390
TYR A 409
 None
 0.97A 2dxrA-4uf7A:
undetectable		 2dxrA-4uf7A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		5 / 10 MET A 281
LEU A 222
ARG A 237
VAL A 302
GLY A 307
 None
None
SO4  A1623 (-2.7A)
None
None
 1.22A 2qd4B-4uf7A:
undetectable		 2qd4B-4uf7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		4 / 7 ILE A 426
ARG A 427
TYR A 375
ASP A 483
 None
 1.12A 2qebB-4uf7A:
undetectable		 2qebB-4uf7A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WB9_A_CYSA301_0
(GLUTATHIONE
TRANSFERASE SIGMA
CLASS)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		4 / 5 TYR A 602
GLY A 221
ARG A 599
TYR A 223
 None
None
SO4  A1618 (-3.8A)
None
 1.11A 2wb9A-4uf7A:
undetectable		 2wb9A-4uf7A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		5 / 12 TYR A 447
GLY A 449
LEU A 463
PRO A 377
TYR A 485
 None
 1.24A 3mecA-4uf7A:
undetectable		 3mecA-4uf7A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		5 / 11 TYR A 247
ALA A 586
ILE A 585
PHE A 245
THR A 517
 None
 1.42A 3qelA-4uf7A:
undetectable
3qelB-4uf7A:
undetectable		 3qelA-4uf7A:
17.91
3qelB-4uf7A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		4 / 4 PHE A 309
TYR A 247
ILE A 361
LEU A 312
 None
 1.46A 3sudA-4uf7A:
undetectable		 3sudA-4uf7A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		4 / 4 ASN A 224
SER A 288
LEU A 265
THR A 226
 None
 1.44A 4an2A-4uf7A:
0.9		 4an2A-4uf7A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		4 / 8 PRO A 204
ASN A 207
GLN A 554
ILE A 549
 None
NAG  A1632 (-1.9A)
None
None
 1.04A 4iilA-4uf7A:
undetectable		 4iilA-4uf7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		3 / 3 ARG A 280
GLU A 273
PHE A 578
 None
 0.91A 4kszA-4uf7A:
undetectable		 4kszA-4uf7A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		3 / 3 ASN A 544
PHE A 559
TYR A 603
 None
ACT  A1626 (-3.5A)
None
 0.88A 4u15A-4uf7A:
undetectable		 4u15A-4uf7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		4 / 7 ASP A 520
THR A 572
THR A 239
SER A 574
 None
 1.35A 5b6iA-4uf7A:
undetectable		 5b6iA-4uf7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		4 / 6 ASP A 520
THR A 572
THR A 239
SER A 574
 None
 1.36A 5b6iB-4uf7A:
undetectable		 5b6iB-4uf7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		5 / 12 TYR A 247
ALA A 586
ILE A 585
PHE A 245
THR A 517
 None
 1.42A 5ewjC-4uf7A:
undetectable
5ewjD-4uf7A:
undetectable		 5ewjC-4uf7A:
18.71
5ewjD-4uf7A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		3 / 3 TYR A 464
TYR A 409
SER A 469
 None
 0.97A 5iktB-4uf7A:
undetectable		 5iktB-4uf7A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 4uf7 GLYCOPROTEIN
(Ghanaian
bat
henipavirus) 		4 / 4 VAL A 344
LEU A 374
ASN A 433
ASP A 432
 None
 1.31A 5vcyA-4uf7A:
undetectable		 5vcyA-4uf7A:
20.57