SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ufc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4ufc GH95
(Bacteroides
ovatus) 		3 / 3 TRP A 561
ALA A 507
VAL A 498
 None
 0.91A 1bdwA-4ufcA:
undetectable
1bdwB-4ufcA:
undetectable		 1bdwA-4ufcA:
2.47
1bdwB-4ufcA:
2.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 10 ALA A  46
THR A 143
THR A 158
ILE A 167
GLY A  50
 None
 1.11A 1c9sN-4ufcA:
undetectable
1c9sO-4ufcA:
undetectable		 1c9sN-4ufcA:
6.66
1c9sO-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 ALA A  46
THR A 143
THR A 158
ILE A 167
GLY A  50
 None
 1.10A 1c9sP-4ufcA:
undetectable
1c9sQ-4ufcA:
undetectable		 1c9sP-4ufcA:
6.66
1c9sQ-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 9 ALA A  46
THR A 143
THR A 158
ILE A 167
GLY A  50
 None
 1.12A 1c9sQ-4ufcA:
undetectable
1c9sR-4ufcA:
undetectable		 1c9sQ-4ufcA:
6.66
1c9sR-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 10 GLY A  50
ALA A  46
THR A 143
THR A 158
ILE A 167
 None
 1.14A 1c9sL-4ufcA:
undetectable
1c9sV-4ufcA:
undetectable		 1c9sL-4ufcA:
6.66
1c9sV-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 12 ILE A 639
ALA A 329
LEU A 303
ALA A 680
ILE A 635
 None
 1.30A 1g5yB-4ufcA:
undetectable		 1g5yB-4ufcA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ufc GH95
(Bacteroides
ovatus) 		5 / 9 GLY A  50
ALA A  46
THR A 143
THR A 158
ILE A 167
 None
 1.19A 1gtfD-4ufcA:
undetectable
1gtfE-4ufcA:
undetectable		 1gtfD-4ufcA:
6.66
1gtfE-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 ALA A  46
THR A 143
THR A 158
ILE A 167
GLY A  50
 None
 1.13A 1gtfQ-4ufcA:
undetectable
1gtfR-4ufcA:
undetectable		 1gtfQ-4ufcA:
6.66
1gtfR-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ufc GH95
(Bacteroides
ovatus) 		5 / 9 ALA A  46
THR A 143
THR A 158
ILE A 167
GLY A  50
 None
 1.11A 1gtfR-4ufcA:
undetectable
1gtfS-4ufcA:
undetectable		 1gtfR-4ufcA:
6.66
1gtfS-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 ALA A  46
THR A 143
THR A 158
ILE A 167
GLY A  50
 None
 1.14A 1gtfS-4ufcA:
undetectable
1gtfT-4ufcA:
undetectable		 1gtfS-4ufcA:
6.66
1gtfT-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 6 LEU A 457
GLY A 713
LYS A 462
TYR A 456
 None
 1.12A 1gtiC-4ufcA:
1.7		 1gtiC-4ufcA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 5 LEU A 457
GLY A 713
LYS A 462
TYR A 456
 None
 1.12A 1gtiF-4ufcA:
1.7		 1gtiF-4ufcA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 7 ALA A  46
THR A 143
THR A 158
ILE A 167
 None
 0.79A 1gtnA-4ufcA:
undetectable
1gtnK-4ufcA:
undetectable		 1gtnA-4ufcA:
6.66
1gtnK-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 ALA A  46
THR A 143
THR A 158
ILE A 167
GLY A  50
 None
 1.10A 1gtnT-4ufcA:
undetectable
1gtnU-4ufcA:
undetectable		 1gtnT-4ufcA:
6.66
1gtnU-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNF_A_EDTA400_0
(IRON-UTILIZATION
PERIPLASMIC PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 GLN A 454
GLU A 383
ASN A 620
TYR A 582
ARG A 712
 None
 1.45A 1nnfA-4ufcA:
0.0		 1nnfA-4ufcA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 8 GLU A 282
THR A 144
ILE A 168
TYR A 248
 None
 0.81A 1qvtA-4ufcA:
undetectable		 1qvtA-4ufcA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 6 LEU A 457
ALA A 766
LEU A 764
SER A 737
 None
 0.87A 1tz8C-4ufcA:
undetectable
1tz8D-4ufcA:
undetectable		 1tz8C-4ufcA:
10.28
1tz8D-4ufcA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 10 ALA A  46
THR A 143
THR A 158
ILE A 167
GLY A  50
 None
 1.09A 1utdU-4ufcA:
undetectable
1utdV-4ufcA:
undetectable		 1utdU-4ufcA:
6.66
1utdV-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 GLY A  50
ALA A  46
THR A 143
THR A 158
ILE A 167
 None
 1.14A 1utdL-4ufcA:
undetectable
1utdV-4ufcA:
undetectable		 1utdL-4ufcA:
6.66
1utdV-4ufcA:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 7 LEU A 331
LEU A  24
PHE A 296
SER A 342
 None
 0.91A 1wrlE-4ufcA:
undetectable
1wrlF-4ufcA:
undetectable		 1wrlE-4ufcA:
8.45
1wrlF-4ufcA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 GLY A 474
GLY A 417
ILE A 515
ALA A 476
ALA A 519
 None
 0.90A 1x7pA-4ufcA:
undetectable
1x7pB-4ufcA:
undetectable		 1x7pA-4ufcA:
18.89
1x7pB-4ufcA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4ufc GH95
(Bacteroides
ovatus) 		3 / 3 ASN A 522
TRP A 453
GLN A 586
 None
 1.42A 1xoqA-4ufcA:
undetectable		 1xoqA-4ufcA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 12 PHE A 296
GLY A 336
LEU A 332
LEU A  22
MET A 328
 None
 1.31A 1ya4B-4ufcA:
undetectable		 1ya4B-4ufcA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 7 LEU A 642
PRO A 665
HIS A 664
GLY A 671
 None
None
GIV  A1809 (-4.0A)
None
 1.04A 2ddwB-4ufcA:
undetectable		 2ddwB-4ufcA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 6 THR A 602
MET A 625
PHE A 596
ILE A 587
 None
 1.44A 2w98B-4ufcA:
undetectable		 2w98B-4ufcA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 7 LEU A 116
GLN A 223
ALA A 245
ILE A 239
 None
 0.69A 2xkwA-4ufcA:
undetectable		 2xkwA-4ufcA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 VAL A 679
LEU A 332
MET A 638
ILE A 639
ALA A 700
 None
 1.19A 2zbzA-4ufcA:
undetectable		 2zbzA-4ufcA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 4ufc GH95
(Bacteroides
ovatus) 		3 / 3 HIS A 451
GLU A 383
HIS A 455
 None
 0.85A 3ba0A-4ufcA:
undetectable		 3ba0A-4ufcA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 8 HIS A 451
ILE A 373
TRP A 447
TRP A 617
 None
 1.19A 3ccfB-4ufcA:
undetectable		 3ccfB-4ufcA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 7 SER A 737
TYR A 456
ASN A 762
LEU A 764
 None
 1.38A 3lslA-4ufcA:
undetectable
3lslD-4ufcA:
undetectable		 3lslA-4ufcA:
15.04
3lslD-4ufcA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_B_ASDB126_1
(STEROID
DELTA-ISOMERASE)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 10 ASN A 352
LEU A 661
PHE A 673
ASN A 378
ALA A 351
 None
 1.45A 3nuvB-4ufcA:
undetectable		 3nuvB-4ufcA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 VAL A 498
PHE A 482
PHE A 478
GLY A 444
GLY A 445
 None
 1.29A 3owxA-4ufcA:
undetectable
3owxB-4ufcA:
undetectable		 3owxA-4ufcA:
13.67
3owxB-4ufcA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 VAL A 498
PHE A 482
PHE A 478
GLY A 445
ILE A 371
 None
 1.37A 3owxA-4ufcA:
undetectable
3owxB-4ufcA:
undetectable		 3owxA-4ufcA:
13.67
3owxB-4ufcA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 9 LEU A 247
THR A 246
VAL A 224
ILE A 239
PHE A 123
 None
 1.20A 3tbgD-4ufcA:
undetectable		 3tbgD-4ufcA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 4 LEU A  37
ILE A 669
TYR A 657
TYR A 338
 None
 1.43A 3vt7A-4ufcA:
undetectable		 3vt7A-4ufcA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 12 ILE A 171
LEU A  44
ILE A 183
ILE A 222
LEU A 273
 None
 1.10A 3w67B-4ufcA:
undetectable		 3w67B-4ufcA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4ufc GH95
(Bacteroides
ovatus) 		3 / 3 ASN A 254
GLU A 265
ARG A 268
 None
 0.99A 3wxoA-4ufcA:
undetectable		 3wxoA-4ufcA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 8 GLN A 454
ASN A 585
GLN A 450
THR A 523
 None
 1.23A 4d1yA-4ufcA:
undetectable
4d1yB-4ufcA:
undetectable		 4d1yA-4ufcA:
13.30
4d1yB-4ufcA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4ufc GH95
(Bacteroides
ovatus) 		5 / 10 GLY A 444
GLY A 445
VAL A 498
PHE A 482
PHE A 478
 None
 1.26A 4fgkA-4ufcA:
undetectable
4fgkB-4ufcA:
undetectable		 4fgkA-4ufcA:
14.71
4fgkB-4ufcA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 6 PRO A 442
ILE A 100
TYR A 413
PHE A 104
 None
 0.99A 4g10A-4ufcA:
1.6		 4g10A-4ufcA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 9 LEU A 694
ILE A 741
ARG A 740
LEU A 739
PHE A 715
 None
 0.94A 4kukA-4ufcA:
undetectable		 4kukA-4ufcA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 12 GLU A 376
ASN A 378
ASP A 670
ASN A 423
ILE A 373
 None
None
None
GIV  A1809 ( 4.6A)
None
 1.13A 4o1eB-4ufcA:
undetectable		 4o1eB-4ufcA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 12 LEU A 684
ALA A 382
ASN A 714
ASN A 734
GLY A 708
 None
 0.89A 4r3aB-4ufcA:
undetectable		 4r3aB-4ufcA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 6 LYS A 546
LEU A 547
ASN A 513
PRO A 548
 None
 1.15A 4yv5B-4ufcA:
undetectable		 4yv5B-4ufcA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 6 LYS A 546
LEU A 547
ASN A 513
PRO A 548
 None
 1.11A 4yv5A-4ufcA:
undetectable		 4yv5A-4ufcA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1729_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 5 GLN A 668
THR A 375
ASP A 670
ASN A 378
 GIV  A1809 ( 4.8A)
None
None
None
 1.38A 5b2qA-4ufcA:
0.0		 5b2qA-4ufcA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 6 ALA A 382
GLN A 345
SER A 343
PRO A 393
 None
 1.05A 5c6pA-4ufcA:
undetectable		 5c6pA-4ufcA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 4ufc GH95
(Bacteroides
ovatus) 		3 / 3 PRO A 188
LEU A  59
SER A 360
 None
 0.72A 5fsaB-4ufcA:
undetectable		 5fsaB-4ufcA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 6 TYR A 657
ASP A 670
ILE A 615
ARG A 655
 None
 1.27A 5igyA-4ufcA:
undetectable		 5igyA-4ufcA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ufc GH95
(Bacteroides
ovatus) 		3 / 3 TYR A 113
TYR A  49
SER A 118
 None
 0.77A 5iktB-4ufcA:
undetectable		 5iktB-4ufcA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 11 ILE A 471
ILE A 452
THR A 475
TRP A 453
ALA A 526
 None
 1.09A 5lg3A-4ufcA:
undetectable		 5lg3A-4ufcA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 4ufc GH95
(Bacteroides
ovatus) 		3 / 3 HIS A 572
ASP A 570
HIS A 502
 None
 0.91A 5n1tW-4ufcA:
undetectable		 5n1tW-4ufcA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 10 LEU A 683
VAL A 299
VAL A 717
GLY A 708
LEU A 301
 None
 1.02A 6bsjA-4ufcA:
undetectable		 6bsjA-4ufcA:
7.18