SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uft'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SN5_C_T3C601_1 (TRANSTHYRETIN)	4uft	NUCLEOPROTEIN (Measles morbillivirus)	4 / 6	LYS B 124 GLU B 124 ALA B 127 LEU B 114	None	1.02A	1sn5A-4uftB: undetectable	1sn5A-4uftB: 16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_A_ACTA501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	4uft	NUCLEOPROTEIN (Measles morbillivirus)	4 / 7	MET B 233 VAL B 178 ARG B 230 ILE B 223	None	1.15A	2yfbA-4uftB: undetectable	2yfbA-4uftB: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I5U_B_SAMB401_1 (O-METHYLTRANSFERASE)	4uft	NUCLEOPROTEIN (Measles morbillivirus)	3 / 3	ASP B 125 PHE B 116 SER B 107	None	1.01A	3i5uB-4uftB: undetectable	3i5uB-4uftB: 24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IMA_D_ADND604_1 (PYRUVATE KINASE)	4uft	NUCLEOPROTEIN (Measles morbillivirus)	3 / 3	ARG B 204 GLU B 252 ASN B 256	None	0.89A	4imaD-4uftB: undetectable	4imaD-4uftB: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_A_C2FA3000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	4uft	NUCLEOPROTEIN (Measles morbillivirus)	5 / 12	ILE B 223 ILE B 88 LEU B 87 GLY B 75 ILE B 74	None	1.03A	4o1eA-4uftB: undetectable	4o1eA-4uftB: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_B_C2FB4000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	4uft	NUCLEOPROTEIN (Measles morbillivirus)	5 / 12	ILE B 223 ILE B 88 LEU B 87 GLY B 75 ILE B 74	None	1.09A	4o1eB-4uftB: undetectable	4o1eB-4uftB: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ACTA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	4uft	NUCLEOPROTEIN (Measles morbillivirus)	4 / 6	PHE B 80 VAL B 81 ILE B 91 ASP B 239	None	1.12A	5iwuA-4uftB: undetectable	5iwuA-4uftB: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W97_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4uft	NUCLEOPROTEIN (Measles morbillivirus)	4 / 6	ARG B 220 LYS B 180 LEU B 177 LEU B 216	None C R 10 ( 3.0A) None None	1.04A	5w97C-4uftB: undetectable 5w97J-4uftB: undetectable	5w97C-4uftB: 20.64 5w97J-4uftB: 13.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SN5_C_T3C601_1","TRANSTHYRETIN;TRANSTHYRETIN","4uft","NUCLEOPROTEIN","Measles morbillivirus",4,"LYS B 124;GLU B 124;ALA B 127;LEU B 114","None","1.02A","1sn5A-4uftB:undetectable","1sn5A-4uftB:16.80"],["2YFB_A_ACTA501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","4uft","NUCLEOPROTEIN","Measles morbillivirus",4,"MET B 233;VAL B 178;ARG B 230;ILE B 223","None","1.15A","2yfbA-4uftB:undetectable","2yfbA-4uftB:21.43"],["3I5U_B_SAMB401_1","O-METHYLTRANSFERASE","4uft","NUCLEOPROTEIN","Measles morbillivirus",3,"ASP B 125;PHE B 116;SER B 107","None","1.01A","3i5uB-4uftB:undetectable","3i5uB-4uftB:24.21"],["4IMA_D_ADND604_1","PYRUVATE KINASE","4uft","NUCLEOPROTEIN","Measles morbillivirus",3,"ARG B 204;GLU B 252;ASN B 256","None","0.89A","4imaD-4uftB:undetectable","4imaD-4uftB:23.05"],["4O1E_A_C2FA3000_0","DIHYDROPTEROATE SYNTHASE DHPS","4uft","NUCLEOPROTEIN","Measles morbillivirus",5,"ILE B 223;ILE B  88;LEU B  87;GLY B  75;ILE B  74","None","1.03A","4o1eA-4uftB:undetectable","4o1eA-4uftB:22.28"],["4O1E_B_C2FB4000_0","DIHYDROPTEROATE SYNTHASE DHPS","4uft","NUCLEOPROTEIN","Measles morbillivirus",5,"ILE B 223;ILE B  88;LEU B  87;GLY B  75;ILE B  74","None","1.09A","4o1eB-4uftB:undetectable","4o1eB-4uftB:22.28"],["5IWU_A_ACTA402_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","4uft","NUCLEOPROTEIN","Measles morbillivirus",4,"PHE B  80;VAL B  81;ILE B  91;ASP B 239","None","1.12A","5iwuA-4uftB:undetectable","5iwuA-4uftB:21.59"],["5W97_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4uft","NUCLEOPROTEIN","Measles morbillivirus",4,"ARG B 220;LYS B 180;LEU B 177;LEU B 216","None;  C R  10 ( 3.0A);None;None","1.04A","5w97C-4uftB:undetectable;5w97J-4uftB:undetectable","5w97C-4uftB:20.64;5w97J-4uftB:13.97"]]