SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uht'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4uht TRANSCRIPTIONAL
REGULATORY PROTEIN
CPXR
(Escherichia
coli) 		4 / 8 PHE A 218
HIS A 200
LEU A 157
THR A 158
 None
 0.80A 1azmA-4uhtA:
undetectable		 1azmA-4uhtA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4uht TRANSCRIPTIONAL
REGULATORY PROTEIN
CPXR
(Escherichia
coli) 		4 / 8 PHE A 218
HIS A 200
LEU A 157
THR A 158
 None
 0.78A 1bzmA-4uhtA:
undetectable		 1bzmA-4uhtA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 4uht TRANSCRIPTIONAL
REGULATORY PROTEIN
CPXR
(Escherichia
coli) 		3 / 3 ALA A 169
VAL A 229
TRP A 217
 None
 0.94A 1grmA-4uhtA:
undetectable		 1grmA-4uhtA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 4uht TRANSCRIPTIONAL
REGULATORY PROTEIN
CPXR
(Escherichia
coli) 		3 / 3 ALA A 169
VAL A 229
TRP A 217
 None
 0.94A 1grmB-4uhtA:
undetectable		 1grmB-4uhtA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 4uht TRANSCRIPTIONAL
REGULATORY PROTEIN
CPXR
(Escherichia
coli) 		5 / 12 ASP A 194
LEU A 186
LYS A 188
ILE A 201
LEU A 164
 None
 1.33A 1lhuA-4uhtA:
undetectable		 1lhuA-4uhtA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 4uht TRANSCRIPTIONAL
REGULATORY PROTEIN
CPXR
(Escherichia
coli) 		4 / 6 GLN A 183
LEU A 181
GLU A 184
LEU A 167
 None
 0.85A 3h5gA-4uhtA:
undetectable
3h5gC-4uhtA:
undetectable		 3h5gA-4uhtA:
13.83
3h5gC-4uhtA:
13.83