SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KCE_A_D16A566_1 (THYMIDYLATE SYNTHASE)	4uj7	SURFACE LAYER PROTEIN (Geobacillus stearothermophil us)	5 / 12	SER A 562 ASP A 684 GLY A 687 VAL A 645 ALA A 646	None	1.33A	2kceA-4uj7A: undetectable	2kceA-4uj7A: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGK_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	4uj7	SURFACE LAYER PROTEIN (Geobacillus stearothermophil us)	3 / 3	VAL A 680 TYR A 653 GLN A 654	None	0.64A	5qgkA-4uj7A: undetectable	5qgkA-4uj7A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGR_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	4uj7	SURFACE LAYER PROTEIN (Geobacillus stearothermophil us)	3 / 3	VAL A 680 TYR A 653 GLN A 654	None	0.66A	5qgrA-4uj7A: undetectable	5qgrA-4uj7A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGT_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	4uj7	SURFACE LAYER PROTEIN (Geobacillus stearothermophil us)	3 / 3	VAL A 680 TYR A 653 GLN A 654	None	0.65A	5qgtA-4uj7A: undetectable	5qgtA-4uj7A: 19.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2KCE_A_D16A566_1","THYMIDYLATE SYNTHASE","4uj7","SURFACE LAYER PROTEIN","Geobacillus stearothermophilus",5,"SER A 562;ASP A 684;GLY A 687;VAL A 645;ALA A 646","None","1.33A","2kceA-4uj7A:undetectable","2kceA-4uj7A:19.32"],["5QGK_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","4uj7","SURFACE LAYER PROTEIN","Geobacillus stearothermophilus",3,"VAL A 680;TYR A 653;GLN A 654","None","0.64A","5qgkA-4uj7A:undetectable","5qgkA-4uj7A:19.91"],["5QGR_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","4uj7","SURFACE LAYER PROTEIN","Geobacillus stearothermophilus",3,"VAL A 680;TYR A 653;GLN A 654","None","0.66A","5qgrA-4uj7A:undetectable","5qgrA-4uj7A:19.91"],["5QGT_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","4uj7","SURFACE LAYER PROTEIN","Geobacillus stearothermophilus",3,"VAL A 680;TYR A 653;GLN A 654","None","0.65A","5qgtA-4uj7A:undetectable","5qgtA-4uj7A:19.91"]]