SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uj8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 4uj8 SURFACE LAYER
PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 12 PHE A 863
LEU A 816
LEU A 787
ALA A 784
ILE A 846
 None
 1.10A 2bxpA-4uj8A:
undetectable		 2bxpA-4uj8A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4uj8 SURFACE LAYER
PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 786
ASN A 789
LEU A 787
ALA A 788
LEU A 774
 None
 1.19A 4ltwA-4uj8A:
undetectable		 4ltwA-4uj8A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)		 4uj8 SURFACE LAYER
PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 LYS A 812
LYS A 768
ALA A 788
 None
 1.49A 4ot2A-4uj8A:
undetectable		 4ot2A-4uj8A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 4uj8 SURFACE LAYER
PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 774
VAL A 851
ILE A 831
ASN A 789
LEU A 771
 None
 1.23A 4yvpB-4uj8A:
undetectable		 4yvpB-4uj8A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 4uj8 SURFACE LAYER
PROTEIN
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 859
VAL A 876
ILE A 772
LEU A 816
LEU A 790
 None
 1.10A 4yvpB-4uj8A:
undetectable		 4yvpB-4uj8A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4uj8 SURFACE LAYER
PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 VAL A 680
TYR A 653
GLN A 654
 None
 0.75A 5qgkA-4uj8A:
undetectable		 5qgkA-4uj8A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4uj8 SURFACE LAYER
PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 VAL A 680
TYR A 653
GLN A 654
 None
 0.75A 5qgtA-4uj8A:
undetectable		 5qgtA-4uj8A:
23.11