SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4umf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 4umf 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE KDSC
(Moraxella
catarrhalis) 		5 / 9 ILE A 108
GLY A 124
TYR A 140
ALA A 150
GLU A 153
 None
 1.20A 1mrgA-4umfA:
undetectable		 1mrgA-4umfA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 4umf 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE KDSC
(Moraxella
catarrhalis) 		5 / 12 ALA A  58
LEU A  13
ILE A  11
ILE A  55
LEU A  91
 None
 1.01A 1xdkF-4umfA:
undetectable		 1xdkF-4umfA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4umf 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE KDSC
(Moraxella
catarrhalis) 		5 / 12 GLU A 156
PHE A 168
ILE A 108
LEU A  22
GLY A 149
 None
 1.32A 2ogyB-4umfA:
undetectable		 2ogyB-4umfA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 4umf 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE KDSC
(Moraxella
catarrhalis) 		5 / 10 ASP A 110
VAL A 127
ILE A  21
GLY A 147
THR A 143
 MG  A1175 (-2.8A)
None
None
None
None
 1.10A 3el5A-4umfA:
undetectable		 3el5A-4umfA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 4umf 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE KDSC
(Moraxella
catarrhalis) 		5 / 12 ILE A 125
LEU A  50
LEU A  47
GLY A  46
ILE A  21
 None
 0.89A 4c9lB-4umfA:
undetectable		 4c9lB-4umfA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4umf 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE KDSC
(Moraxella
catarrhalis) 		4 / 4 ILE A  21
SER A  23
ASP A 114
ASP A  86
 None
None
MG  A1175 ( 4.3A)
None
 1.47A 4krhB-4umfA:
undetectable		 4krhB-4umfA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 4umf 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE KDSC
(Moraxella
catarrhalis) 		5 / 9 ILE A 108
GLY A 124
TYR A 140
ALA A 150
GLU A 153
 None
 1.25A 5cf9B-4umfA:
undetectable		 5cf9B-4umfA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 4umf 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE KDSC
(Moraxella
catarrhalis) 		5 / 12 ASP A  43
ALA A  38
GLY A  20
GLY A 147
SER A 126
 None
None
MG  A1175 ( 4.7A)
None
None
 1.27A 6clxA-4umfA:
2.7		 6clxA-4umfA:
22.74