SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4umi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 4umi FIBER PROTEIN
(Snake
atadenovirus
A) 		4 / 8 GLN A 249
ASN A 250
LEU A 281
SER A 277
 None
 1.01A 1hk3A-4umiA:
undetectable		 1hk3A-4umiA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4umi FIBER PROTEIN
(Snake
atadenovirus
A) 		4 / 5 PHE A 256
LEU A 331
PHE A 258
SER A 339
 None
 1.22A 1wrlC-4umiA:
undetectable		 1wrlC-4umiA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 4umi FIBER PROTEIN
(Snake
atadenovirus
A) 		4 / 7 PHE A 285
PHE A 258
ILE A 307
GLY A 278
 None
 0.90A 2v0mC-4umiA:
undetectable		 2v0mC-4umiA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 4umi FIBER PROTEIN
(Snake
atadenovirus
A) 		4 / 7 GLU A 264
ARG A 271
GLU A 262
SER A 241
 None
 1.11A 2zt7A-4umiA:
undetectable		 2zt7A-4umiA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 4umi FIBER PROTEIN
(Snake
atadenovirus
A) 		4 / 5 THR A 282
GLY A 280
VAL A 334
PRO A 332
 None
 1.14A 4grkA-4umiA:
undetectable		 4grkA-4umiA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 4umi FIBER PROTEIN
(Snake
atadenovirus
A) 		4 / 6 GLU A 264
ARG A 271
GLU A 262
SER A 241
 None
 0.97A 4kr3A-4umiA:
undetectable		 4kr3A-4umiA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 4umi FIBER PROTEIN
(Snake
atadenovirus
A) 		5 / 12 ALA A 275
GLY A 337
VAL A 334
PHE A 258
LEU A 248
 None
 1.16A 5w7pA-4umiA:
undetectable		 5w7pA-4umiA:
22.47