SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uoh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4uoh NUCLEOSIDE
DIPHOSPHATE KINASE
(Litopenaeus
vannamei) 		5 / 12 THR A   6
GLY A 118
SER A 119
VAL A  10
ILE A 115
 None
 0.98A 2b25B-4uohA:
undetectable		 2b25B-4uohA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4uoh NUCLEOSIDE
DIPHOSPHATE KINASE
(Litopenaeus
vannamei) 		5 / 12 GLY A  81
GLY A  79
GLY A  31
GLU A  78
VAL A  83
 None
 0.99A 2oxtC-4uohA:
undetectable		 2oxtC-4uohA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 4uoh NUCLEOSIDE
DIPHOSPHATE KINASE
(Litopenaeus
vannamei) 		4 / 6 HIS A 117
GLU A 128
ASP A 120
SER A 124
 None
 1.19A 4apjA-4uohA:
undetectable
4apjP-4uohA:
undetectable		 4apjA-4uohA:
14.16
4apjP-4uohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 4uoh NUCLEOSIDE
DIPHOSPHATE KINASE
(Litopenaeus
vannamei) 		4 / 7 GLY A 118
ALA A 125
SER A 119
GLU A   4
 None
 0.91A 4hyfA-4uohA:
undetectable		 4hyfA-4uohA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 4uoh NUCLEOSIDE
DIPHOSPHATE KINASE
(Litopenaeus
vannamei) 		4 / 8 GLY A 118
ALA A 125
SER A 119
GLU A   4
 None
 0.91A 4hyfB-4uohA:
undetectable		 4hyfB-4uohA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 4uoh NUCLEOSIDE
DIPHOSPHATE KINASE
(Litopenaeus
vannamei) 		3 / 4 SER A  98
GLY A 118
GLU A   4
 None
 0.61A 4juoA-4uohA:
2.2
4juoC-4uohA:
undetectable		 4juoA-4uohA:
16.09
4juoC-4uohA:
13.68