SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		5 / 7 GLY A 272
PRO A 271
THR A 276
ILE A 269
GLY A 274
 None
 1.10A 1usqA-4uokA:
undetectable		 1usqA-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 GLY A 272
PRO A 271
ILE A 269
GLY A 274
 None
 0.84A 1usqB-4uokA:
undetectable		 1usqB-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 GLY A 272
PRO A 271
ILE A 269
GLY A 274
 None
 0.83A 1usqC-4uokA:
undetectable		 1usqC-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 GLY A 272
PRO A 271
ILE A 269
GLY A 274
 None
 0.84A 1usqD-4uokA:
undetectable		 1usqD-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 GLY A 272
PRO A 271
ILE A 269
GLY A 274
 None
 0.83A 1usqE-4uokA:
undetectable		 1usqE-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		5 / 7 GLY A 272
PRO A 271
THR A 276
ILE A 269
GLY A 274
 None
 1.13A 2jklA-4uokA:
undetectable		 2jklA-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		5 / 7 GLY A 272
PRO A 271
THR A 276
ILE A 269
GLY A 274
 None
 1.13A 2jklC-4uokA:
undetectable		 2jklC-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		5 / 7 GLY A 272
PRO A 271
THR A 276
ILE A 269
GLY A 274
 None
 1.12A 2jklD-4uokA:
undetectable		 2jklD-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		5 / 7 GLY A 272
PRO A 271
THR A 276
ILE A 269
GLY A 274
 None
 1.13A 2jklF-4uokA:
undetectable		 2jklF-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 SER A 317
LEU A 263
MET A 255
 None
 0.70A 5ikrB-4uokA:
undetectable		 5ikrB-4uokA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4uok FAB FRAGMENT HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 GLU A 369
PHE A 367
HIS A 421
THR A 331
 None
 1.06A 6b58A-4uokA:
undetectable		 6b58A-4uokA:
16.03