SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uon'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 4uon CAPSID PROTEASE
(Aura
virus) 		3 / 3 TRP A 250
TYR A 165
LEU A 234
 None
 1.04A 1kxhA-4uonA:
undetectable		 1kxhA-4uonA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 4uon CAPSID PROTEASE
(Aura
virus) 		4 / 6 SER A 162
TYR A 165
VAL A 248
TRP A 250
 None
 1.48A 2x45A-4uonA:
undetectable		 2x45A-4uonA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4uon CAPSID PROTEASE
(Aura
virus) 		3 / 3 ARG A 220
HIS A 195
TYR A 131
 None
 0.89A 4fu8A-4uonA:
9.7		 4fu8A-4uonA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4uon CAPSID PROTEASE
(Aura
virus) 		3 / 3 ARG A 220
HIS A 196
TYR A 131
 None
 1.22A 4fu8A-4uonA:
9.7		 4fu8A-4uonA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4uon CAPSID PROTEASE
(Aura
virus) 		3 / 3 ARG A 220
HIS A 195
TYR A 131
 None
 0.92A 4fu9A-4uonA:
9.7		 4fu9A-4uonA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4uon CAPSID PROTEASE
(Aura
virus) 		3 / 3 ARG A 220
HIS A 196
TYR A 131
 None
 1.12A 4fu9A-4uonA:
9.7		 4fu9A-4uonA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4uon CAPSID PROTEASE
(Aura
virus) 		4 / 5 GLU A 136
THR A 118
HIS A 195
LEU A 223
 None
 1.26A 5axaC-4uonA:
undetectable		 5axaC-4uonA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 4uon CAPSID PROTEASE
(Aura
virus) 		5 / 12 ILE A 128
PHE A 119
GLY A 147
ALA A 134
ASP A 150
 None
 1.04A 5e72A-4uonA:
undetectable		 5e72A-4uonA:
17.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5G4B_A_PZEA1268_1
(CAPSID PROTEIN)		 4uon CAPSID PROTEASE
(Aura
virus) 		4 / 5 MET A 135
GLU A 136
TYR A 183
TRP A 250
 None
 0.63A 5g4bA-4uonA:
27.5		 5g4bA-4uonA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4uon CAPSID PROTEASE
(Aura
virus) 		4 / 5 PRO A 221
VAL A 133
GLY A 254
VAL A 248
 None
 1.04A 6ak3B-4uonA:
undetectable		 6ak3B-4uonA:
19.73