SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 4uqf GTP CYCLOHYDROLASE 1
(Listeria
monocytogenes) 		3 / 3 ARG A 108
HIS A  54
SER A 104
 None
 0.87A 4mjwA-4uqfA:
undetectable
4mjwB-4uqfA:
undetectable		 4mjwA-4uqfA:
18.46
4mjwB-4uqfA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 4uqf GTP CYCLOHYDROLASE 1
(Listeria
monocytogenes) 		3 / 3 SER A 104
ARG A 108
HIS A  54
 None
 0.95A 4mjwA-4uqfA:
undetectable
4mjwB-4uqfA:
undetectable		 4mjwA-4uqfA:
18.46
4mjwB-4uqfA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4uqf GTP CYCLOHYDROLASE 1
(Listeria
monocytogenes) 		5 / 9 VAL A  69
LEU A 106
ALA A 107
ASP A 111
VAL A 142
 None
 0.86A 5om2A-4uqfA:
undetectable
5om2B-4uqfA:
undetectable		 5om2A-4uqfA:
21.36
5om2B-4uqfA:
9.74