SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ure'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 9 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.48A 1c9sM-4ureA:
undetectable
1c9sN-4ureA:
undetectable		 1c9sM-4ureA:
17.32
1c9sN-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.07A 1c9sN-4ureA:
undetectable
1c9sO-4ureA:
undetectable		 1c9sN-4ureA:
17.32
1c9sO-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 11 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.07A 1c9sP-4ureA:
undetectable
1c9sQ-4ureA:
undetectable		 1c9sP-4ureA:
17.32
1c9sQ-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 9 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.07A 1c9sQ-4ureA:
undetectable
1c9sR-4ureA:
undetectable		 1c9sQ-4ureA:
17.32
1c9sR-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 9 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.49A 1c9sS-4ureA:
undetectable
1c9sT-4ureA:
undetectable		 1c9sS-4ureA:
17.32
1c9sT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.04A 1c9sL-4ureA:
undetectable
1c9sV-4ureA:
undetectable		 1c9sL-4ureA:
17.32
1c9sV-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		4 / 8 GLU A 205
ARG A 202
ARG A 201
LEU A 213
 None
 0.77A 1cmaA-4ureA:
undetectable
1cmaB-4ureA:
undetectable		 1cmaA-4ureA:
21.26
1cmaB-4ureA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 9 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.03A 1gtfD-4ureA:
undetectable
1gtfE-4ureA:
undetectable		 1gtfD-4ureA:
17.32
1gtfE-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 1gtfJ-4ureA:
undetectable
1gtfK-4ureA:
undetectable		 1gtfJ-4ureA:
17.32
1gtfK-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 9 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.49A 1gtfO-4ureA:
undetectable
1gtfP-4ureA:
undetectable		 1gtfO-4ureA:
17.32
1gtfP-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.48A 1gtfP-4ureA:
undetectable
1gtfQ-4ureA:
undetectable		 1gtfP-4ureA:
17.32
1gtfQ-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 11 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.05A 1gtfQ-4ureA:
undetectable
1gtfR-4ureA:
undetectable		 1gtfQ-4ureA:
17.32
1gtfR-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 9 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.07A 1gtfR-4ureA:
undetectable
1gtfS-4ureA:
undetectable		 1gtfR-4ureA:
17.32
1gtfS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 11 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.04A 1gtfS-4ureA:
undetectable
1gtfT-4ureA:
undetectable		 1gtfS-4ureA:
17.32
1gtfT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 1gtfT-4ureA:
undetectable
1gtfU-4ureA:
undetectable		 1gtfT-4ureA:
17.32
1gtfU-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		4 / 6 SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 0.81A 1gtnD-4ureA:
undetectable
1gtnE-4ureA:
undetectable		 1gtnD-4ureA:
17.32
1gtnE-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 9 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.35A 1gtnR-4ureA:
undetectable
1gtnS-4ureA:
undetectable		 1gtnR-4ureA:
17.32
1gtnS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 11 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.04A 1gtnT-4ureA:
undetectable
1gtnU-4ureA:
undetectable		 1gtnT-4ureA:
17.32
1gtnU-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 12 GLY A  12
GLY A  14
ILE A  37
ASP A  62
ILE A 113
 None
 0.70A 1qaoA-4ureA:
6.0		 1qaoA-4ureA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 12 ALA A 224
MET A   1
VAL A  32
LYS A   6
ALA A   8
 None
 1.05A 1sa1A-4ureA:
5.6
1sa1B-4ureA:
6.7		 1sa1A-4ureA:
21.54
1sa1B-4ureA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 12 ALA A 224
MET A   1
VAL A  32
LYS A   6
ALA A   8
 None
 1.03A 1sa1C-4ureA:
6.7
1sa1D-4ureA:
6.8		 1sa1C-4ureA:
21.54
1sa1D-4ureA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.03A 1utdE-4ureA:
undetectable
1utdF-4ureA:
undetectable		 1utdE-4ureA:
17.32
1utdF-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.03A 1utdH-4ureA:
undetectable
1utdI-4ureA:
undetectable		 1utdH-4ureA:
17.32
1utdI-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.26A 1utdR-4ureA:
undetectable
1utdS-4ureA:
undetectable		 1utdR-4ureA:
17.32
1utdS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 11 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.06A 1utdS-4ureA:
undetectable
1utdT-4ureA:
undetectable		 1utdS-4ureA:
17.32
1utdT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 148
THR A 156
ILE A 149
GLY A 161
SER A 141
 None
 1.08A 1utdU-4ureA:
undetectable
1utdV-4ureA:
undetectable		 1utdU-4ureA:
17.32
1utdV-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 11 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.04A 1utdL-4ureA:
undetectable
1utdV-4ureA:
undetectable		 1utdL-4ureA:
17.32
1utdV-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		3 / 3 LEU A  23
LEU A   2
MET A   1
 None
 0.70A 2itzA-4ureA:
undetectable		 2itzA-4ureA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 11 ILE A  21
ILE A  17
GLY A  16
VAL A 241
GLY A 214
 None
 1.01A 4ac9B-4ureA:
7.1
4ac9C-4ureA:
7.0		 4ac9B-4ureA:
21.28
4ac9C-4ureA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 12 GLY A  12
GLY A  14
ASP A  36
ILE A  37
ASP A  62
 None
 0.49A 4iv8A-4ureA:
7.1		 4iv8A-4ureA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 12 GLY A  12
GLY A  14
ASP A  36
ILE A  37
ASP A  62
 None
 0.48A 4iv8B-4ureA:
7.2		 4iv8B-4ureA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 12 GLY A  12
GLY A  14
SER A  38
ASP A  62
ILE A 113
 None
 0.75A 4krhA-4ureA:
3.5		 4krhA-4ureA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		6 / 12 GLY A  12
GLY A  14
ILE A  37
SER A  38
ILE A  17
ARG A 109
 None
 1.44A 4qtuB-4ureA:
6.8		 4qtuB-4ureA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		6 / 12 GLY A  12
GLY A  14
ILE A  37
SER A  38
ILE A  17
ARG A 109
 None
 1.48A 4qtuD-4ureA:
7.1		 4qtuD-4ureA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.42A 5eeuN-4ureA:
undetectable
5eeuO-4ureA:
undetectable		 5eeuN-4ureA:
17.32
5eeuO-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5eeuR-4ureA:
undetectable
5eeuS-4ureA:
undetectable		 5eeuR-4ureA:
17.32
5eeuS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5eeuS-4ureA:
undetectable
5eeuT-4ureA:
undetectable		 5eeuS-4ureA:
17.32
5eeuT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5eeuT-4ureA:
undetectable
5eeuU-4ureA:
undetectable		 5eeuT-4ureA:
17.32
5eeuU-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5eeuU-4ureA:
undetectable
5eeuV-4ureA:
undetectable		 5eeuU-4ureA:
17.32
5eeuV-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5eevA-4ureA:
undetectable
5eevB-4ureA:
undetectable		 5eevA-4ureA:
17.32
5eevB-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.42A 5eevN-4ureA:
undetectable
5eevO-4ureA:
undetectable		 5eevN-4ureA:
17.32
5eevO-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5eevR-4ureA:
undetectable
5eevS-4ureA:
undetectable		 5eevR-4ureA:
17.32
5eevS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5eevS-4ureA:
undetectable
5eevT-4ureA:
undetectable		 5eevS-4ureA:
17.32
5eevT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5eevT-4ureA:
undetectable
5eevU-4ureA:
undetectable		 5eevT-4ureA:
17.32
5eevU-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5eewA-4ureA:
undetectable
5eewB-4ureA:
undetectable		 5eewA-4ureA:
17.32
5eewB-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.42A 5eewN-4ureA:
undetectable
5eewO-4ureA:
undetectable		 5eewN-4ureA:
17.32
5eewO-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5eewR-4ureA:
undetectable
5eewS-4ureA:
undetectable		 5eewR-4ureA:
17.32
5eewS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5eewS-4ureA:
undetectable
5eewT-4ureA:
undetectable		 5eewS-4ureA:
17.32
5eewT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5eewT-4ureA:
undetectable
5eewU-4ureA:
undetectable		 5eewT-4ureA:
17.32
5eewU-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5eexA-4ureA:
undetectable
5eexB-4ureA:
undetectable		 5eexA-4ureA:
17.32
5eexB-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.42A 5eexN-4ureA:
undetectable
5eexO-4ureA:
undetectable		 5eexN-4ureA:
17.32
5eexO-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5eexR-4ureA:
undetectable
5eexS-4ureA:
undetectable		 5eexR-4ureA:
17.32
5eexS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5eexS-4ureA:
undetectable
5eexT-4ureA:
undetectable		 5eexS-4ureA:
17.32
5eexT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5eexT-4ureA:
undetectable
5eexU-4ureA:
undetectable		 5eexT-4ureA:
17.32
5eexU-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5eeyA-4ureA:
undetectable
5eeyB-4ureA:
undetectable		 5eeyA-4ureA:
17.32
5eeyB-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.42A 5eeyN-4ureA:
undetectable
5eeyO-4ureA:
undetectable		 5eeyN-4ureA:
17.32
5eeyO-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5eeyR-4ureA:
undetectable
5eeyS-4ureA:
undetectable		 5eeyR-4ureA:
17.32
5eeyS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5eeyS-4ureA:
undetectable
5eeyT-4ureA:
undetectable		 5eeyS-4ureA:
17.32
5eeyT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5eeyT-4ureA:
undetectable
5eeyU-4ureA:
undetectable		 5eeyT-4ureA:
17.32
5eeyU-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5eezA-4ureA:
undetectable
5eezB-4ureA:
undetectable		 5eezA-4ureA:
17.32
5eezB-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.42A 5eezN-4ureA:
undetectable
5eezO-4ureA:
undetectable		 5eezN-4ureA:
17.32
5eezO-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5eezR-4ureA:
undetectable
5eezS-4ureA:
undetectable		 5eezR-4ureA:
17.32
5eezS-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5eezS-4ureA:
undetectable
5eezT-4ureA:
undetectable		 5eezS-4ureA:
17.32
5eezT-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5eezT-4ureA:
undetectable
5eezU-4ureA:
undetectable		 5eezT-4ureA:
17.32
5eezU-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5ef0A-4ureA:
undetectable
5ef0B-4ureA:
undetectable		 5ef0A-4ureA:
17.32
5ef0B-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.43A 5ef0N-4ureA:
undetectable
5ef0O-4ureA:
undetectable		 5ef0N-4ureA:
17.32
5ef0O-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5ef0R-4ureA:
undetectable
5ef0S-4ureA:
undetectable		 5ef0R-4ureA:
17.32
5ef0S-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5ef0S-4ureA:
undetectable
5ef0T-4ureA:
undetectable		 5ef0S-4ureA:
17.32
5ef0T-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5ef0T-4ureA:
undetectable
5ef0U-4ureA:
undetectable		 5ef0T-4ureA:
17.32
5ef0U-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5ef1A-4ureA:
undetectable
5ef1B-4ureA:
undetectable		 5ef1A-4ureA:
17.32
5ef1B-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.43A 5ef1N-4ureA:
undetectable
5ef1O-4ureA:
undetectable		 5ef1N-4ureA:
17.32
5ef1O-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5ef1R-4ureA:
undetectable
5ef1S-4ureA:
undetectable		 5ef1R-4ureA:
17.32
5ef1S-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5ef1S-4ureA:
undetectable
5ef1T-4ureA:
undetectable		 5ef1S-4ureA:
17.32
5ef1T-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.45A 5ef1T-4ureA:
undetectable
5ef1U-4ureA:
undetectable		 5ef1T-4ureA:
17.32
5ef1U-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5ef2A-4ureA:
undetectable
5ef2B-4ureA:
undetectable		 5ef2A-4ureA:
17.32
5ef2B-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.43A 5ef2N-4ureA:
undetectable
5ef2O-4ureA:
undetectable		 5ef2N-4ureA:
17.32
5ef2O-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5ef2R-4ureA:
undetectable
5ef2S-4ureA:
undetectable		 5ef2R-4ureA:
17.32
5ef2S-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5ef2S-4ureA:
undetectable
5ef2T-4ureA:
undetectable		 5ef2S-4ureA:
17.32
5ef2T-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5ef2T-4ureA:
undetectable
5ef2U-4ureA:
undetectable		 5ef2T-4ureA:
17.32
5ef2U-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 161
SER A 141
GLY A 148
THR A 156
ILE A 149
 None
 1.00A 5ef3A-4ureA:
undetectable
5ef3B-4ureA:
undetectable		 5ef3A-4ureA:
17.32
5ef3B-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.43A 5ef3N-4ureA:
undetectable
5ef3O-4ureA:
undetectable		 5ef3N-4ureA:
17.32
5ef3O-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.27A 5ef3R-4ureA:
undetectable
5ef3S-4ureA:
undetectable		 5ef3R-4ureA:
17.32
5ef3S-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
ALA A  90
THR A  63
ILE A 113
 None
 1.28A 5ef3S-4ureA:
undetectable
5ef3T-4ureA:
undetectable		 5ef3S-4ureA:
17.32
5ef3T-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 10 GLY A 117
HIS A  69
THR A  63
ILE A 113
SER A  35
 None
 1.44A 5ef3T-4ureA:
undetectable
5ef3U-4ureA:
undetectable		 5ef3T-4ureA:
17.32
5ef3U-4ureA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 4ure CYCLOHEXANOL
DEHYDROGENASE
(Aromatoleum
aromaticum) 		5 / 12 GLY A  12
GLY A  14
ASP A  36
ILE A  37
ILE A  17
 None
 0.66A 5wy0A-4ureA:
6.2		 5wy0A-4ureA:
21.24