SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 9 TYR A   6
GLY A  73
MET A 183
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
MPD  A 401 (-3.9A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 1.24A 1e9lA-4uriA:
44.0		 1e9lA-4uriA:
31.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		7 / 9 TYR A   6
PHE A  30
GLY A  72
ASP A 114
MET A 183
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.92A 1e9lA-4uriA:
44.0		 1e9lA-4uriA:
31.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		7 / 9 TYR A   6
PHE A  30
GLY A  72
MET A 183
TYR A 185
ASP A 186
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
MPD  A 401 (-3.8A)
 0.85A 1e9lA-4uriA:
44.0		 1e9lA-4uriA:
31.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 11 PHE A  50
ASN A 181
LEU A 111
GLY A 110
PHE A 108
 None
 1.20A 1ju6A-4uriA:
undetectable		 1ju6A-4uriA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		3 / 3 ARG A 135
ILE A 100
TRP A 134
 NA  A 502 ( 4.4A)
None
None
 1.20A 1qomA-4uriA:
undetectable		 1qomA-4uriA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 8 LYS A   1
PHE A 315
PHE A  27
LEU A  67
 None
 0.92A 1v54P-4uriA:
undetectable
1v54W-4uriA:
undetectable		 1v54P-4uriA:
21.51
1v54W-4uriA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		10 / 11 TYR A   6
PHE A  30
GLY A  72
ASP A 114
GLU A 116
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.67A 2a3aA-4uriA:
40.4		 2a3aA-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 9 GLY A  73
GLU A 116
MET A 183
TYR A 185
TRP A 317
 MPD  A 401 (-3.9A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 1.13A 2a3aB-4uriA:
40.7		 2a3aB-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 9 PHE A  30
GLY A  72
GLU A 116
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.61A 2a3aB-4uriA:
40.7		 2a3aB-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 11 TYR A   6
PHE A  30
GLY A  72
ASP A 114
GLU A 116
MET A 183
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.86A 2a3bA-4uriA:
40.4		 2a3bA-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		9 / 11 TYR A   6
PHE A  30
GLY A  72
ASP A 114
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.69A 2a3bA-4uriA:
40.4		 2a3bA-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 10 PHE A  30
GLY A  72
ASP A 114
GLU A 116
MET A 183
TYR A 185
ASP A 186
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
MPD  A 401 (-3.8A)
 0.78A 2a3bB-4uriA:
40.6		 2a3bB-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 10 PHE A  30
GLY A  72
ASP A 114
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.58A 2a3bB-4uriA:
40.6		 2a3bB-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 12 TYR A   6
PHE A  30
GLY A  72
ASP A 114
GLU A 116
MET A 183
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.86A 2a3cA-4uriA:
40.3		 2a3cA-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		9 / 12 TYR A   6
PHE A  30
GLY A  72
ASP A 114
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.69A 2a3cA-4uriA:
40.3		 2a3cA-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 12 PHE A  30
GLY A  72
ASP A 114
GLU A 116
MET A 183
TYR A 185
ASP A 186
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
MPD  A 401 (-3.8A)
 0.78A 2a3cB-4uriA:
40.6		 2a3cB-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 12 PHE A  30
GLY A  72
ASP A 114
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.57A 2a3cB-4uriA:
40.6		 2a3cB-4uriA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		3 / 3 LYS A 302
ASP A 186
ASP A 191
 None
 1.16A 2br4A-4uriA:
undetectable		 2br4A-4uriA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		3 / 3 THR A 163
PRO A 118
TYR A 168
 None
 0.96A 2dxrA-4uriA:
undetectable		 2dxrA-4uriA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		6 / 9 TYR A   6
PHE A  30
GLY A  72
ASP A 114
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.95A 2uy4A-4uriA:
18.9		 2uy4A-4uriA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		6 / 9 TYR A   6
PHE A  30
GLY A  72
GLU A 116
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-2.7A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.45A 2uy4A-4uriA:
18.9		 2uy4A-4uriA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 8 ALA A  47
ALA A  49
GLY A  10
CYH A  28
 None
 0.88A 2vh3B-4uriA:
undetectable		 2vh3B-4uriA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		6 / 11 TYR A   6
PHE A  30
GLY A  72
ASP A 114
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 1.03A 2xtkA-4uriA:
19.7		 2xtkA-4uriA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		6 / 11 TYR A   6
PHE A  30
GLY A  72
GLU A 116
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-2.7A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.67A 2xtkA-4uriA:
19.7		 2xtkA-4uriA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 10 TYR A   6
PHE A  30
GLY A  72
ASP A 114
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-3.8A)
 1.04A 2xtkB-4uriA:
19.9		 2xtkB-4uriA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		6 / 10 TYR A   6
PHE A  30
GLY A  72
GLU A 116
TYR A 185
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-2.7A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.56A 2xtkB-4uriA:
19.9		 2xtkB-4uriA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		3 / 3 VAL A 267
ASN A 324
TRP A 325
 None
 0.95A 2y00B-4uriA:
undetectable		 2y00B-4uriA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 12 TYR A 263
ILE A 266
TYR A 291
VAL A 261
THR A 269
 None
 1.35A 3a8iC-4uriA:
undetectable		 3a8iC-4uriA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 7 LYS A   1
PHE A 315
PHE A  27
LEU A  67
 None
 0.97A 3asoP-4uriA:
undetectable
3asoW-4uriA:
undetectable		 3asoP-4uriA:
21.51
3asoW-4uriA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		3 / 3 ARG A 135
ILE A 100
TRP A 134
 NA  A 502 ( 4.4A)
None
None
 1.16A 3e7iB-4uriA:
undetectable		 3e7iB-4uriA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		10 / 11 TYR A   6
PHE A  30
GLY A  72
ASP A 114
GLU A 116
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 MPD  A 401 (-3.5A)
None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.71A 3g6mA-4uriA:
40.9		 3g6mA-4uriA:
26.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 8 PHE A 315
ASP A 112
TYR A   6
LEU A 229
 None
None
MPD  A 401 (-3.5A)
None
 0.81A 3jq7B-4uriA:
undetectable		 3jq7B-4uriA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 12 ILE A 162
SER A 159
GLY A 158
THR A 184
SER A 211
 None
None
None
None
MPD  A 402 (-2.7A)
 1.39A 3r75A-4uriA:
undetectable		 3r75A-4uriA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 12 ILE A 162
SER A 159
GLY A 158
THR A 184
SER A 211
 None
None
None
None
MPD  A 402 (-2.7A)
 1.40A 3r75B-4uriA:
undetectable		 3r75B-4uriA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		7 / 11 GLY A  73
GLU A 116
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 MPD  A 401 (-3.9A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.96A 3wqvA-4uriA:
42.5		 3wqvA-4uriA:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 11 PHE A  30
GLY A  72
ASP A 114
TYR A 185
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.95A 3wqvA-4uriA:
42.5		 3wqvA-4uriA:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 11 PHE A  30
GLY A  72
GLU A 116
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.45A 3wqvA-4uriA:
42.5		 3wqvA-4uriA:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		7 / 11 GLY A  73
GLU A 116
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 MPD  A 401 (-3.9A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.96A 3wqwA-4uriA:
42.6		 3wqwA-4uriA:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 11 PHE A  30
GLY A  72
ASP A 114
TYR A 185
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-4.3A)
MPD  A 401 (-4.8A)
MPD  A 401 (-3.8A)
 0.96A 3wqwA-4uriA:
42.6		 3wqwA-4uriA:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		8 / 11 PHE A  30
GLY A  72
GLU A 116
MET A 183
TYR A 185
ASP A 186
TYR A 236
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-2.7A)
MPD  A 401 (-3.0A)
MPD  A 401 (-4.8A)
None
None
MPD  A 401 (-3.8A)
 0.47A 3wqwA-4uriA:
42.6		 3wqwA-4uriA:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 7 ILE A  70
VAL A  81
SER A  99
ASP A 123
 None
 1.40A 4iarA-4uriA:
undetectable		 4iarA-4uriA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 4 PHE A  30
ASP A 112
GLY A  72
SER A  69
 None
None
MPD  A 401 ( 4.6A)
None
 1.33A 4xp9C-4uriA:
undetectable		 4xp9C-4uriA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 12 GLY A 170
TYR A 168
TYR A 167
ALA A 172
ASN A 176
 None
 1.29A 4ymgA-4uriA:
undetectable		 4ymgA-4uriA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 12 GLY A 170
TYR A 168
TYR A 167
ALA A 172
ASN A 176
 None
 1.30A 4ymgB-4uriA:
undetectable		 4ymgB-4uriA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		3 / 3 VAL A 182
ALA A 155
PHE A 315
 None
MPD  A 401 (-3.4A)
None
 0.85A 4z4iA-4uriA:
2.3		 4z4iA-4uriA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 8 GLY A 249
THR A 195
TRP A 240
TYR A 188
 None
 1.00A 5flcB-4uriA:
undetectable		 5flcB-4uriA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 8 GLY A 249
THR A 195
TRP A 240
TYR A 188
 None
 1.00A 5flcF-4uriA:
undetectable		 5flcF-4uriA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 8 GLY A  73
GLU A 116
TYR A 185
ASP A 186
TRP A 317
 MPD  A 401 (-3.9A)
MPD  A 401 (-2.7A)
MPD  A 401 (-4.8A)
None
MPD  A 401 (-3.8A)
 1.13A 5gqbA-4uriA:
39.7		 5gqbA-4uriA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		6 / 8 PHE A  30
GLY A  72
GLU A 116
TYR A 185
ASP A 186
TRP A 317
 None
MPD  A 401 ( 4.6A)
MPD  A 401 (-2.7A)
MPD  A 401 (-4.8A)
None
MPD  A 401 (-3.8A)
 0.59A 5gqbA-4uriA:
39.7		 5gqbA-4uriA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		4 / 8 ALA A 155
ASP A 112
LEU A  67
TYR A 185
 MPD  A 401 (-3.4A)
None
None
MPD  A 401 (-4.8A)
 0.84A 5uihA-4uriA:
undetectable		 5uihA-4uriA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 11 ASP A 294
LEU A 231
GLY A 336
LEU A 203
GLN A 308
 None
 1.21A 6euqA-4uriA:
undetectable		 6euqA-4uriA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		3 / 3 ARG A 284
PHE A 285
GLY A 271
 None
 0.76A 6fgdA-4uriA:
undetectable		 6fgdA-4uriA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 4uri CHITINASE-RELATED
AGGLUTININ
(Robinia
pseudoacacia) 		5 / 11 PHE A  50
ASN A 181
LEU A 111
GLY A 110
PHE A 108
 None
 1.20A 6r2eG-4uriA:
undetectable		 6r2eG-4uriA:
21.32