SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4urj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_A_ACTA501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	4urj	PROTEIN FAM83A (Homo sapiens)	4 / 7	ARG A 148 VAL A 151 ILE A 155 TYR A 257	None EDO A1305 ( 4.3A) None None	0.96A	2yfbA-4urjA: undetectable	2yfbA-4urjA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_A_ACTA501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	4urj	PROTEIN FAM83A (Homo sapiens)	4 / 7	VAL A 151 ARG A 152 ILE A 155 TYR A 257	EDO A1305 ( 4.3A) None None None	1.05A	2yfbA-4urjA: undetectable	2yfbA-4urjA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_B_ACTB501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	4urj	PROTEIN FAM83A (Homo sapiens)	4 / 6	ARG A 148 VAL A 151 ILE A 155 TYR A 257	None EDO A1305 ( 4.3A) None None	0.94A	2yfbB-4urjA: undetectable	2yfbB-4urjA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_B_ACTB501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	4urj	PROTEIN FAM83A (Homo sapiens)	4 / 6	ASP A 171 ARG A 148 VAL A 151 TYR A 257	None None EDO A1305 ( 4.3A) None	1.17A	2yfbB-4urjA: undetectable	2yfbB-4urjA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_B_ACTB501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	4urj	PROTEIN FAM83A (Homo sapiens)	4 / 6	VAL A 151 ARG A 152 ILE A 155 TYR A 257	EDO A1305 ( 4.3A) None None None	1.13A	2yfbB-4urjA: undetectable	2yfbB-4urjA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WSJ_A_MK1A201_1 (PROTEASE)	4urj	PROTEIN FAM83A (Homo sapiens)	5 / 9	LEU A 215 ASP A 177 VAL A 189 LEU A 162 ILE A 218	None	1.04A	3wsjA-4urjA: undetectable	3wsjA-4urjA: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	4urj	PROTEIN FAM83A (Homo sapiens)	4 / 4	GLN A 140 THR A 141 THR A 136 LEU A 253	None None None EDO A1305 ( 4.8A)	1.47A	5m5kA-4urjA: undetectable	5m5kA-4urjA: 17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_C_ADNC502_2 (ADENOSYLHOMOCYSTEINA SE)	4urj	PROTEIN FAM83A (Homo sapiens)	4 / 4	GLN A 140 THR A 141 THR A 136 LEU A 253	None None None EDO A1305 ( 4.8A)	1.45A	5m5kC-4urjA: undetectable	5m5kC-4urjA: 17.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YFB_A_ACTA501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","4urj","PROTEIN FAM83A","Homo sapiens",4,"ARG A 148;VAL A 151;ILE A 155;TYR A 257","None;EDO A1305 ( 4.3A);None;None","0.96A","2yfbA-4urjA:undetectable","2yfbA-4urjA:20.38"],["2YFB_A_ACTA501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","4urj","PROTEIN FAM83A","Homo sapiens",4,"VAL A 151;ARG A 152;ILE A 155;TYR A 257","EDO A1305 ( 4.3A);None;None;None","1.05A","2yfbA-4urjA:undetectable","2yfbA-4urjA:20.38"],["2YFB_B_ACTB501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","4urj","PROTEIN FAM83A","Homo sapiens",4,"ARG A 148;VAL A 151;ILE A 155;TYR A 257","None;EDO A1305 ( 4.3A);None;None","0.94A","2yfbB-4urjA:undetectable","2yfbB-4urjA:20.38"],["2YFB_B_ACTB501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","4urj","PROTEIN FAM83A","Homo sapiens",4,"ASP A 171;ARG A 148;VAL A 151;TYR A 257","None;None;EDO A1305 ( 4.3A);None","1.17A","2yfbB-4urjA:undetectable","2yfbB-4urjA:20.38"],["2YFB_B_ACTB501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","4urj","PROTEIN FAM83A","Homo sapiens",4,"VAL A 151;ARG A 152;ILE A 155;TYR A 257","EDO A1305 ( 4.3A);None;None;None","1.13A","2yfbB-4urjA:undetectable","2yfbB-4urjA:20.38"],["3WSJ_A_MK1A201_1","PROTEASE","4urj","PROTEIN FAM83A","Homo sapiens",5,"LEU A 215;ASP A 177;VAL A 189;LEU A 162;ILE A 218","None","1.04A","3wsjA-4urjA:undetectable","3wsjA-4urjA:21.16"],["5M5K_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","4urj","PROTEIN FAM83A","Homo sapiens",4,"GLN A 140;THR A 141;THR A 136;LEU A 253","None;None;None;EDO A1305 ( 4.8A)","1.47A","5m5kA-4urjA:undetectable","5m5kA-4urjA:17.29"],["5M5K_C_ADNC502_2","ADENOSYLHOMOCYSTEINASE","4urj","PROTEIN FAM83A","Homo sapiens",4,"GLN A 140;THR A 141;THR A 136;LEU A 253","None;None;None;EDO A1305 ( 4.8A)","1.45A","5m5kC-4urjA:undetectable","5m5kC-4urjA:17.29"]]