SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4urp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  99
LYS A 105
ARG A 108
 None
 1.16A 1ra8A-4urpA:
undetectable		 1ra8A-4urpA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 VAL A  52
SER A  50
LEU A 100
PHE A 117
 None
 1.15A 2f78A-4urpA:
undetectable		 2f78A-4urpA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 VAL A  52
SER A  50
LEU A 100
PHE A 117
 None
 1.23A 2f8dA-4urpA:
undetectable		 2f8dA-4urpA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 145
ASN A 144
LEU A 136
TYR A 148
 None
 1.15A 2w8yA-4urpA:
undetectable		 2w8yA-4urpA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  20
VAL A  59
GLY A  92
VAL A  94
LEU A  30
 None
 1.15A 3dh0A-4urpA:
undetectable		 3dh0A-4urpA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 171
LEU A 141
PHE A  96
ILE A  57
VAL A  33
 None
 1.01A 3w68A-4urpA:
undetectable		 3w68A-4urpA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4jksA-4urpA:
undetectable		 4jksA-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4jksB-4urpA:
undetectable		 4jksB-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4k8cB-4urpA:
undetectable		 4k8cB-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4k8kB-4urpA:
undetectable		 4k8kB-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4kahA-4urpA:
undetectable		 4kahA-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.06A 4kahB-4urpA:
undetectable		 4kahB-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4kanA-4urpA:
undetectable		 4kanA-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4kanB-4urpA:
undetectable		 4kanB-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4kbeA-4urpA:
undetectable		 4kbeA-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.05A 4lbgA-4urpA:
undetectable		 4lbgA-4urpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4urp FATTY ACID
REPRESSION MUTANT
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
GLY A 126
ILE A  40
THR A 134
THR A  44
 None
 1.06A 4lcaB-4urpA:
undetectable		 4lcaB-4urpA:
21.45