SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4urq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)
4urq DIGUANYLATE CYCLASE
(Thermotoga
maritima)
3 / 3 PHE U 121
LEU U 187
SER U 246
None
0.70A 1e7aA-4urqU:
undetectable
1e7aA-4urqU:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4urq DIGUANYLATE CYCLASE
(Thermotoga
maritima)
3 / 3 GLU U 170
TYR U 166
PHE U 124
None
0.78A 1eqbB-4urqU:
undetectable
1eqbB-4urqU:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4urq DIGUANYLATE CYCLASE
(Thermotoga
maritima)
3 / 3 GLU U 170
TYR U 166
PHE U 124
None
0.79A 1eqbA-4urqU:
undetectable
1eqbA-4urqU:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4urq DIGUANYLATE CYCLASE
(Thermotoga
maritima)
3 / 3 GLU U 170
TYR U 166
PHE U 124
None
0.79A 1eqbD-4urqU:
undetectable
1eqbD-4urqU:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4urq DIGUANYLATE CYCLASE
(Thermotoga
maritima)
3 / 3 GLU U 170
TYR U 166
PHE U 124
None
0.79A 1eqbC-4urqU:
undetectable
1eqbC-4urqU:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
4urq DIGUANYLATE CYCLASE
(Thermotoga
maritima)
5 / 10 GLY U 142
VAL U 145
GLU U 144
ASN U 134
ILE U 133
None
1.43A 3uayA-4urqU:
undetectable
3uayA-4urqU:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
4urq DIGUANYLATE CYCLASE
(Thermotoga
maritima)
5 / 12 LEU U 175
VAL U 122
VAL U 157
LEU U  96
VAL U 125
None
1.25A 4ib4A-4urqU:
undetectable
4ib4A-4urqU:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
4urq DIGUANYLATE CYCLASE
(Thermotoga
maritima)
5 / 12 LEU U 175
VAL U 122
VAL U 157
LEU U  96
VAL U 125
None
1.25A 4nc3A-4urqU:
undetectable
4nc3A-4urqU:
14.98