SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4usc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		4 / 8 HIS A 169
GLY A 172
LEU A 245
ASP A 248
 HEM  A1318 (-3.3A)
HEM  A1318 (-3.1A)
HEM  A1318 (-4.8A)
None
 0.42A 1aegA-4uscA:
24.4		 1aegA-4uscA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		4 / 6 VAL A  22
GLY A  21
ALA A 104
LEU A  36
 None
 0.62A 1e7bB-4uscA:
2.0		 1e7bB-4uscA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		3 / 3 GLY A  51
ASP A 125
SER A  96
 None
 0.71A 3brfA-4uscA:
undetectable		 3brfA-4uscA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 12 LEU A 101
GLY A  35
GLY A 172
ALA A 105
ILE A 171
 None
HEM  A1318 (-3.4A)
HEM  A1318 (-3.1A)
None
None
 0.98A 3ku1G-4uscA:
undetectable		 3ku1G-4uscA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 11 VAL A 287
LEU A 288
LEU A   2
GLY A  51
ALA A  98
 None
 1.16A 3pghB-4uscA:
undetectable		 3pghB-4uscA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 9 VAL A 287
LEU A 288
LEU A   2
GLY A  51
ALA A  98
 None
 1.12A 4rs0A-4uscA:
1.8		 4rs0A-4uscA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		4 / 8 ARG A 123
ALA A 102
LEU A 101
GLY A  51
 None
 1.01A 4xk8a-4uscA:
undetectable		 4xk8a-4uscA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DL9_A_ACTA214_0
(LYSOZYME C)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		4 / 5 GLU A 274
ASP A 160
TRP A 271
ALA A 270
 None
None
None
NAG  A1311 (-3.2A)
 1.45A 5dl9A-4uscA:
undetectable		 5dl9A-4uscA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eeuF-4uscA:
undetectable
5eeuG-4uscA:
undetectable		 5eeuF-4uscA:
13.01
5eeuG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eevF-4uscA:
undetectable
5eevG-4uscA:
undetectable		 5eevF-4uscA:
13.01
5eevG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eewF-4uscA:
undetectable
5eewG-4uscA:
undetectable		 5eewF-4uscA:
13.01
5eewG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eexF-4uscA:
undetectable
5eexG-4uscA:
undetectable		 5eexF-4uscA:
13.01
5eexG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eeyF-4uscA:
undetectable
5eeyG-4uscA:
undetectable		 5eeyF-4uscA:
13.01
5eeyG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.17A 5eezF-4uscA:
undetectable
5eezG-4uscA:
undetectable		 5eezF-4uscA:
13.01
5eezG-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.18A 5ef0F-4uscA:
undetectable
5ef0G-4uscA:
undetectable		 5ef0F-4uscA:
13.01
5ef0G-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.18A 5ef1F-4uscA:
undetectable
5ef1G-4uscA:
undetectable		 5ef1F-4uscA:
13.01
5ef1G-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.18A 5ef2F-4uscA:
undetectable
5ef2G-4uscA:
undetectable		 5ef2F-4uscA:
13.01
5ef2G-4uscA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usc PEROXIDASE
(Trachycarpus
fortunei) 		5 / 10 ALA A 105
GLY A  76
ALA A 104
HIS A  42
ILE A  80
 None
SO4  A1316 (-3.9A)
None
PEO  A1320 (-3.6A)
None
 1.18A 5ef3F-4uscA:
undetectable
5ef3G-4uscA:
undetectable		 5ef3F-4uscA:
13.01
5ef3G-4uscA:
13.01