SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4usi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4usi NITROGEN REGULATORY
PROTEIN PII
(Chlamydomonas
reinhardtii) 		5 / 10 ARG A  29
THR A  36
ALA A  97
ALA A  96
ILE A 109
 None
 1.23A 1gtnB-4usiA:
undetectable
1gtnC-4usiA:
undetectable		 1gtnB-4usiA:
25.17
1gtnC-4usiA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4usi NITROGEN REGULATORY
PROTEIN PII
(Chlamydomonas
reinhardtii) 		5 / 10 ARG A  29
THR A  36
ALA A  97
ALA A  96
ILE A 109
 None
 1.20A 1gtnH-4usiA:
undetectable
1gtnI-4usiA:
undetectable		 1gtnH-4usiA:
25.17
1gtnI-4usiA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usi NITROGEN REGULATORY
PROTEIN PII
(Chlamydomonas
reinhardtii) 		5 / 12 ARG A  29
THR A  36
ALA A  97
ALA A  96
ILE A 109
 None
 1.16A 5eeuI-4usiA:
undetectable
5eeuJ-4usiA:
undetectable		 5eeuI-4usiA:
25.17
5eeuJ-4usiA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usi NITROGEN REGULATORY
PROTEIN PII
(Chlamydomonas
reinhardtii) 		5 / 12 ARG A  29
THR A  36
ALA A  97
ALA A  96
ILE A 109
 None
 1.16A 5eevI-4usiA:
undetectable
5eevJ-4usiA:
undetectable		 5eevI-4usiA:
25.17
5eevJ-4usiA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4usi NITROGEN REGULATORY
PROTEIN PII
(Chlamydomonas
reinhardtii) 		5 / 12 ARG A  29
THR A  36
ALA A  97
ALA A  96
ILE A 109
 None
 1.16A 5eewI-4usiA:
undetectable
5eewJ-4usiA:
undetectable		 5eewI-4usiA:
25.17
5eewJ-4usiA:
25.17