SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4usp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF502_2 (PHOSPHOLIPASE A2)	4usp	CCL2 LECTIN (Coprinopsis cinerea)	4 / 5	ILE A 76 SER A 67 PRO A 68 PRO A 72	None	1.42A	3bjwC-4uspA: undetectable	3bjwC-4uspA: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DOU_A_SAMA1_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	4usp	CCL2 LECTIN (Coprinopsis cinerea)	5 / 12	GLY A 135 GLY A 102 GLY A 101 GLN A 106 ALA A 131	None	0.76A	3douA-4uspA: undetectable	3douA-4uspA: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1Y_D_LOCD502_2 (TUBULIN BETA CHAIN)	4usp	CCL2 LECTIN (Coprinopsis cinerea)	5 / 12	LEU A 20 LEU A 44 THR A 30 VAL A 138 ILE A 14	None	1.06A	4x1yD-4uspA: undetectable	4x1yD-4uspA: 16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DLV_B_5D5B927_0 (ECTONUCLEOTIDE PYROPHOSPHATASE/PHOS PHODIESTERASE FAMILY MEMBER 2)	4usp	CCL2 LECTIN (Coprinopsis cinerea)	5 / 12	LEU A 54 ASP A 45 PRO A 84 ILE A 127 VAL A 142	None	1.39A	5dlvB-4uspA: undetectable	5dlvB-4uspA: 10.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJW_F_SVRF502_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","4usp","CCL2 LECTIN","Coprinopsis cinerea",4,"ILE A  76;SER A  67;PRO A  68;PRO A  72","None","1.42A","3bjwC-4uspA:undetectable","3bjwC-4uspA:20.69"],["3DOU_A_SAMA1_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","4usp","CCL2 LECTIN","Coprinopsis cinerea",5,"GLY A 135;GLY A 102;GLY A 101;GLN A 106;ALA A 131","None","0.76A","3douA-4uspA:undetectable","3douA-4uspA:18.09"],["4X1Y_D_LOCD502_2","TUBULIN BETA CHAIN","4usp","CCL2 LECTIN","Coprinopsis cinerea",5,"LEU A  20;LEU A  44;THR A  30;VAL A 138;ILE A  14","None","1.06A","4x1yD-4uspA:undetectable","4x1yD-4uspA:16.78"],["5DLV_B_5D5B927_0","ECTONUCLEOTIDE PYROPHOSPHATASE\/PHOSPHODIESTERASE FAMILY MEMBER 2","4usp","CCL2 LECTIN","Coprinopsis cinerea",5,"LEU A  54;ASP A  45;PRO A  84;ILE A 127;VAL A 142","None","1.39A","5dlvB-4uspA:undetectable","5dlvB-4uspA:10.76"]]