SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4utf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		3 / 3 ASN A 298
ARG A 295
ASP A 196
 MAN  A 511 (-3.4A)
MAN  A 511 ( 3.1A)
MAN  A 510 (-2.8A)
 0.90A 2qe6A-4utfA:
undetectable		 2qe6A-4utfA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		3 / 3 ASN A 298
ARG A 295
ASP A 196
 MAN  A 511 (-3.4A)
MAN  A 511 ( 3.1A)
MAN  A 510 (-2.8A)
 0.91A 2qe6B-4utfA:
undetectable		 2qe6B-4utfA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		4 / 7 GLU A 156
TYR A 198
TYR A 250
PHE A  44
 IFM  A 501 (-2.8A)
MAN  A 510 (-4.5A)
None
None
 1.35A 3ku9B-4utfA:
undetectable		 3ku9B-4utfA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		3 / 3 LYS A 379
ARG A 376
ASP A 187
 None
 1.30A 3o7wA-4utfA:
undetectable		 3o7wA-4utfA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		5 / 10 THR A 329
PHE A  44
SER A 284
TYR A 250
PHE A 253
 None
None
None
None
MAN  A 510 (-4.6A)
 1.49A 3u9fI-4utfA:
undetectable		 3u9fI-4utfA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		3 / 3 GLN A 339
PHE A  91
TYR A 356
 None
 0.82A 3ucjB-4utfA:
undetectable		 3ucjB-4utfA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		3 / 3 GLN A 339
PHE A  91
TYR A 356
 None
 0.84A 3ucjA-4utfA:
undetectable		 3ucjA-4utfA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		4 / 7 THR A 329
HIS A 154
TYR A 195
LEU A 229
 None
IFM  A 501 (-4.1A)
IFM  A 501 ( 3.6A)
None
 1.15A 4awuA-4utfA:
4.3		 4awuA-4utfA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		5 / 12 GLY A 286
GLY A 337
GLY A 288
HIS A 335
GLU A 336
 None
None
None
MAN  A 500 (-4.5A)
IFM  A 501 ( 2.8A)
 0.90A 4ctjC-4utfA:
undetectable		 4ctjC-4utfA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		3 / 3 LEU A 365
MET A 115
ASP A  47
 None
 0.71A 4j7xB-4utfA:
undetectable		 4j7xB-4utfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		3 / 3 GLU A 341
TRP A 334
LYS A 108
 None
 0.86A 4k7aA-4utfA:
undetectable		 4k7aA-4utfA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		4 / 4 HIS A 335
GLU A 156
HIS A 154
LEU A 121
 MAN  A 500 (-4.5A)
IFM  A 501 (-2.8A)
IFM  A 501 (-4.1A)
None
 1.42A 4m2rA-4utfA:
undetectable		 4m2rA-4utfA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		3 / 3 ARG A 161
THR A 124
TRP A 126
 None
None
EDO  A1002 (-3.7A)
 1.25A 4ug5A-4utfA:
undetectable		 4ug5A-4utfA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		5 / 12 GLY A 286
GLY A 337
GLY A 288
HIS A 335
GLU A 336
 None
None
None
MAN  A 500 (-4.5A)
IFM  A 501 ( 2.8A)
 0.91A 5ekxB-4utfA:
undetectable		 5ekxB-4utfA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		5 / 12 PHE A 193
ILE A 227
PHE A  44
THR A 259
GLU A 156
 None
None
None
None
IFM  A 501 (-2.8A)
 1.20A 5vcgA-4utfA:
undetectable		 5vcgA-4utfA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		5 / 12 GLY A 286
GLY A 337
GLY A 288
HIS A 335
GLU A 336
 None
None
None
MAN  A 500 (-4.5A)
IFM  A 501 ( 2.8A)
 0.85A 5wz1B-4utfA:
undetectable		 5wz1B-4utfA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4utf GLYCOSYL HYDROLASE
FAMILY 71
(Bacteroides
xylanisolvens) 		4 / 6 GLY A  50
ASP A  55
SER A 101
ARG A 136
 None
 0.81A 6dwdA-4utfA:
undetectable
6dwdC-4utfA:
undetectable		 6dwdA-4utfA:
20.11
6dwdC-4utfA:
20.11