SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4utg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
4 / 8 PHE A 177
VAL A  34
GLY A  20
GLY A  19
None
None
None
CL  A 401 (-3.5A)
0.88A 1ekjE-4utgA:
undetectable
1ekjF-4utgA:
undetectable
1ekjE-4utgA:
20.81
1ekjF-4utgA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
4 / 8 ALA A 292
PHE A 308
VAL A 310
VAL A 203
None
0.63A 1epbB-4utgA:
undetectable
1epbB-4utgA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
4 / 4 THR A 321
LEU A 318
VAL A 203
LEU A 202
None
0.97A 1mz9D-4utgA:
undetectable
1mz9D-4utgA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 10 LEU A 133
ALA A 129
LEU A 136
ILE A  91
LEU A 104
None
1.31A 1pcgA-4utgA:
undetectable
1pcgA-4utgA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.28A 1v8bB-4utgA:
undetectable
1v8bB-4utgA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.30A 1v8bD-4utgA:
undetectable
1v8bD-4utgA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 307
GLY A 115
GLY A 299
GLY A  19
LYS A 268
None
ANP  A 399 ( 3.0A)
ANP  A 399 (-3.7A)
CL  A 401 (-3.5A)
CL  A 402 ( 4.0A)
1.10A 1y4lA-4utgA:
undetectable
1y4lA-4utgA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 11 ALA A  10
ALA A  43
LEU A 122
ALA A 167
ILE A  47
None
1.09A 2aclE-4utgA:
undetectable
2aclE-4utgA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 11 GLY A 115
SER A 210
ILE A 216
SER A 213
ALA A 272
ANP  A 399 ( 3.0A)
None
None
ANP  A 399 (-3.0A)
None
1.06A 2nnhA-4utgA:
undetectable
2nnhA-4utgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
4 / 7 GLY A 304
GLY A 303
SER A 114
LEU A 116
None
None
MG  A 400 (-2.4A)
MG  A 400 ( 4.6A)
0.80A 2oa1B-4utgA:
undetectable
2oa1B-4utgA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.29A 3ce6A-4utgA:
undetectable
3ce6A-4utgA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.30A 3ce6C-4utgA:
undetectable
3ce6C-4utgA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.29A 3g1uA-4utgA:
undetectable
3g1uA-4utgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.28A 3g1uB-4utgA:
undetectable
3g1uB-4utgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.26A 3g1uC-4utgA:
undetectable
3g1uC-4utgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.28A 3g1uD-4utgA:
undetectable
3g1uD-4utgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 10 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.29A 3h9uD-4utgA:
undetectable
3h9uD-4utgA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.24A 3n58A-4utgA:
undetectable
3n58A-4utgA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 133
ALA A 129
LEU A 136
ILE A 100
LEU A 104
None
1.17A 3olsB-4utgA:
undetectable
3olsB-4utgA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
4 / 6 SER A 166
TYR A 165
ALA A 167
ARG A  13
None
EDO  A1347 (-4.7A)
None
ANP  A 399 (-3.0A)
1.11A 3rd0A-4utgA:
undetectable
3rd0A-4utgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 SER A 271
GLY A  19
GLY A 299
ALA A 300
GLY A  20
None
CL  A 401 (-3.5A)
ANP  A 399 (-3.7A)
ANP  A 399 (-4.0A)
None
1.17A 3tegA-4utgA:
2.1
3tegA-4utgA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
4 / 7 ALA A 234
ILE A 238
ARG A 240
GLY A 264
None
0.95A 3v4tH-4utgA:
undetectable
3v4tH-4utgA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 9 THR A 207
GLY A 115
PHE A 305
SER A 298
GLY A 301
None
ANP  A 399 ( 3.0A)
None
None
None
1.32A 4kqiA-4utgA:
undetectable
4kqiA-4utgA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 GLY A  15
GLY A 299
LEU A  35
ASN A  36
LEU A 198
CL  A 402 ( 3.7A)
ANP  A 399 (-3.7A)
None
None
None
1.02A 4n49A-4utgA:
undetectable
4n49A-4utgA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A  82
LEU A 104
MET A 126
VAL A 125
THR A  60
None
1.40A 4okbA-4utgA:
undetectable
4okbA-4utgA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.28A 4pfjA-4utgA:
undetectable
4pfjA-4utgA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 THR A 335
GLY A 171
ASN A 173
HIS A 333
ASN A 337
None
1.34A 4pooB-4utgA:
undetectable
4pooB-4utgA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.25A 5axaA-4utgA:
undetectable
5axaA-4utgA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.25A 5axaC-4utgA:
undetectable
5axaC-4utgA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 GLY A 160
GLY A 117
LEU A  12
GLY A  18
VAL A  34
None
ANP  A 399 ( 3.5A)
None
CL  A 401 (-4.4A)
None
1.27A 5i71A-4utgA:
undetectable
5i71A-4utgA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 ASP A  22
GLY A  20
MET A 235
ALA A 231
ASN A 223
None
1.21A 5kc4E-4utgA:
undetectable
5kc4E-4utgA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.26A 5m5kA-4utgA:
undetectable
5m5kA-4utgA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.26A 5m5kC-4utgA:
undetectable
5m5kC-4utgA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.25A 5m66A-4utgA:
undetectable
5m66A-4utgA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.23A 5m66B-4utgA:
undetectable
5m66B-4utgA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.25A 5v96A-4utgA:
undetectable
5v96A-4utgA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.26A 5v96B-4utgA:
undetectable
5v96B-4utgA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.26A 5v96C-4utgA:
undetectable
5v96C-4utgA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.25A 5v96D-4utgA:
undetectable
5v96D-4utgA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 GLY A 301
VAL A 275
ALA A 272
GLY A  20
VAL A  23
None
0.90A 5xv7A-4utgA:
undetectable
5xv7A-4utgA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
4 / 6 GLY A 301
SER A 114
THR A 207
VAL A 297
None
MG  A 400 (-2.4A)
None
None
1.15A 5ysiA-4utgA:
undetectable
5ysiA-4utgA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
6 / 10 ALA A  37
LEU A 202
LEU A 307
LEU A 249
MET A 245
LEU A 198
None
1.30A 6f5uA-4utgA:
undetectable
6f5uB-4utgA:
undetectable
6f5uA-4utgA:
14.16
6f5uB-4utgA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.29A 6gbnA-4utgA:
undetectable
6gbnA-4utgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 198
LEU A  14
GLY A  15
MET A 261
PHE A 257
None
None
CL  A 402 ( 3.7A)
None
None
1.28A 6gbnD-4utgA:
undetectable
6gbnD-4utgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)
4utg SUGAR KINASE
(Burkholderia
pseudomallei)
5 / 12 LEU A 249
ILE A 190
GLY A 171
PHE A 172
ASN A 173
None
1.27A 6qyaD-4utgA:
undetectable
6qyaD-4utgA:
23.34