SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4utt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		4 / 5 ARG A 215
THR A 185
LEU A 189
ALA A 205
 None
 1.42A 2e1qD-4uttA:
undetectable		 2e1qD-4uttA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		4 / 7 GLN A 157
TYR A 154
TYR A  75
ILE A  74
 None
None
ACT  A1223 (-4.6A)
None
 1.32A 2ph9A-4uttA:
undetectable
2ph9B-4uttA:
undetectable		 2ph9A-4uttA:
19.28
2ph9B-4uttA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA504_0
(CHORISMATE SYNTHASE)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		4 / 5 SER A 155
ARG A 182
LEU A 148
SER A 149
 None
 1.36A 2qhfA-4uttA:
undetectable		 2qhfA-4uttA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		4 / 5 ARG A  43
ASP A 126
ILE A 127
GLU A 180
 CL  A1221 (-3.9A)
None
None
None
 1.07A 2xrzA-4uttA:
undetectable
2xrzB-4uttA:
undetectable		 2xrzA-4uttA:
21.10
2xrzB-4uttA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		4 / 4 ILE A  61
ARG A 208
ILE A  42
THR A  89
 None
ACT  A1223 (-4.8A)
None
None
 0.99A 3ia4C-4uttA:
undetectable		 3ia4C-4uttA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		5 / 12 GLY A 133
THR A 172
SER A 149
ASP A  97
ALA A  98
 None
 0.98A 3id6C-4uttA:
undetectable		 3id6C-4uttA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		4 / 6 ASP A 194
LEU A 195
ALA A 200
LEU A 189
 None
 1.07A 3rozA-4uttA:
undetectable		 3rozA-4uttA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		3 / 3 ARG A 101
ASP A  97
TYR A  75
 None
None
ACT  A1223 (-4.6A)
 0.87A 4yo9B-4uttA:
undetectable		 4yo9B-4uttA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		5 / 12 GLN A  14
ALA A  34
LEU A 189
ILE A 178
MET A 124
 CL  A1221 (-3.4A)
None
None
None
None
 1.19A 5hv1A-4uttA:
2.2		 5hv1A-4uttA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		5 / 9 ASN A  51
ASP A  49
ILE A  42
GLY A  63
ILE A  94
 None
 1.29A 5kr2A-4uttA:
undetectable		 5kr2A-4uttA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		5 / 9 ASN A  51
ASP A  49
ILE A  42
GLY A  63
ILE A  94
 None
 1.16A 5kr2C-4uttA:
undetectable		 5kr2C-4uttA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		4 / 7 ASP A  49
GLY A  46
HIS A  22
ASN A  48
 None
 1.00A 5nnwD-4uttA:
undetectable		 5nnwD-4uttA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 4utt PUTATIVE
N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE
(Clostridium
perfringens) 		3 / 3 ASP A 126
LEU A 148
ARG A 182
 None
 0.59A 7dfrA-4uttA:
undetectable		 7dfrA-4uttA:
22.73