SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uu2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4uu2 FERULIC ACID
DECARBOXYLASE
(Enterobacter
sp.) 		3 / 3 ARG A 142
ASP A  38
ASN A 148
 None
 0.87A 2zzmA-4uu2A:
undetectable		 2zzmA-4uu2A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1226_0
(THAUMATIN-LIKE
PROTEIN)		 4uu2 FERULIC ACID
DECARBOXYLASE
(Enterobacter
sp.) 		4 / 5 GLU A 149
ASP A  38
ASN A 111
PHE A 109
 None
 1.34A 3zs3A-4uu2A:
0.0		 3zs3A-4uu2A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 4uu2 FERULIC ACID
DECARBOXYLASE
(Enterobacter
sp.) 		3 / 3 GLU A  28
ARG A  40
HIS A  42
 None
 0.86A 4kf9A-4uu2A:
undetectable		 4kf9A-4uu2A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA608_0
(SERUM ALBUMIN)		 4uu2 FERULIC ACID
DECARBOXYLASE
(Enterobacter
sp.) 		4 / 4 PRO A 164
ASP A 165
LEU A 167
ARG A 142
 None
 1.02A 4luhA-4uu2A:
undetectable		 4luhA-4uu2A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 4uu2 FERULIC ACID
DECARBOXYLASE
(Enterobacter
sp.) 		3 / 3 LYS A  15
VAL A 141
ASP A 143
 None
 0.68A 6fgdA-4uu2A:
undetectable		 6fgdA-4uu2A:
15.95