SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uu5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 4uu5 MAGUK P55 SUBFAMILY
MEMBER 5
(Homo
sapiens) 		4 / 7 ILE A 307
ILE A 309
VAL A 317
LEU A 320
 None
 0.62A 3r9vA-4uu5A:
undetectable
3r9vB-4uu5A:
undetectable		 3r9vA-4uu5A:
13.84
3r9vB-4uu5A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4uu5 MAGUK P55 SUBFAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 LEU A 321
ALA A 269
ASN A 305
ILE A 280
VAL A 301
 None
 0.95A 4nkxA-4uu5A:
undetectable		 4nkxA-4uu5A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4uu5 MAGUK P55 SUBFAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 LEU A 321
ALA A 269
ASN A 305
ILE A 280
VAL A 301
 None
 1.06A 4nkxC-4uu5A:
undetectable		 4nkxC-4uu5A:
13.83