SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uuk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4uuk DYNAMIN-1
(Homo
sapiens) 		5 / 12 SER B 668
ASP B 667
ASP B 492
ALA B 408
ILE B 412
 None
 1.35A 1s14B-4uukB:
undetectable		 1s14B-4uukB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4uuk DYNAMIN-1
(Homo
sapiens) 		4 / 8 LYS B 419
ARG B 678
GLN B 416
MET B 670
 None
 1.43A 3dh0A-4uukB:
undetectable		 3dh0A-4uukB:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4uuk DYNAMIN-1
(Homo
sapiens) 		4 / 7 SER B 437
LEU B 701
ILE B 464
PHE B 696
 None
 1.01A 3ln1C-4uukB:
undetectable		 3ln1C-4uukB:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4uuk DYNAMIN-1
(Homo
sapiens) 		4 / 5 ARG B 385
ASP B 667
GLU B 387
VAL B 417
 None
 1.46A 4nkvB-4uukB:
undetectable		 4nkvB-4uukB:
20.67