SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XF1_B_ACTB1108_0 (C5A PEPTIDASE)	4uur	PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN (Pseudoalteromona s haloplanktis)	4 / 6	LEU A 73 ASN A 39 ILE A 37 PHE A 41	None	0.90A	1xf1B-4uurA: undetectable	1xf1B-4uurA: 9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRC_A_CHDA703_0 (FERROCHELATASE)	4uur	PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN (Pseudoalteromona s haloplanktis)	4 / 4	LEU A 54 PRO A 53 LEU A 105 ARG A 106	HEM A 700 (-4.7A) None HEM A 700 ( 4.3A) None	1.30A	2hrcA-4uurA: undetectable	2hrcA-4uurA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_B_CHDB1_0 (FERROCHELATASE, MITOCHONDRIAL)	4uur	PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN (Pseudoalteromona s haloplanktis)	4 / 4	LEU A 54 PRO A 53 LEU A 105 ARG A 106	HEM A 700 (-4.7A) None HEM A 700 ( 4.3A) None	1.22A	3hcoB-4uurA: undetectable	3hcoB-4uurA: 17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HHJ_A_GLYA403_0 (RETRON-TYPE REVERSE TRANSCRIPTASE)	4uur	PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN (Pseudoalteromona s haloplanktis)	4 / 4	LEU A 117 LEU A 126 GLY A 129 GLU A 128	None	1.17A	5hhjA-4uurA: undetectable	5hhjA-4uurA: 18.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XF1_B_ACTB1108_0","C5A PEPTIDASE","4uur","PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN","Pseudoalteromonas haloplanktis",4,"LEU A  73;ASN A  39;ILE A  37;PHE A  41","None","0.90A","1xf1B-4uurA:undetectable","1xf1B-4uurA:9.72"],["2HRC_A_CHDA703_0","FERROCHELATASE","4uur","PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN","Pseudoalteromonas haloplanktis",4,"LEU A  54;PRO A  53;LEU A 105;ARG A 106","HEM A 700 (-4.7A);None;HEM A 700 ( 4.3A);None","1.30A","2hrcA-4uurA:undetectable","2hrcA-4uurA:18.57"],["3HCO_B_CHDB1_0","FERROCHELATASE, MITOCHONDRIAL","4uur","PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN","Pseudoalteromonas haloplanktis",4,"LEU A  54;PRO A  53;LEU A 105;ARG A 106","HEM A 700 (-4.7A);None;HEM A 700 ( 4.3A);None","1.22A","3hcoB-4uurA:undetectable","3hcoB-4uurA:17.60"],["5HHJ_A_GLYA403_0","RETRON-TYPE REVERSE TRANSCRIPTASE","4uur","PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN","Pseudoalteromonas haloplanktis",4,"LEU A 117;LEU A 126;GLY A 129;GLU A 128","None","1.17A","5hhjA-4uurA:undetectable","5hhjA-4uurA:18.15"]]