SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 4uut HOMEOTIC PROTEIN
ULTRABITHORAX
(Drosophila
melanogaster) 		5 / 12 THR A  22
ASN A  23
HIS A  24
ILE A  45
LEU A  40
 None
 1.16A 1r30B-4uutA:
undetectable		 1r30B-4uutA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 4uut HOMEOTIC PROTEIN
ULTRABITHORAX
(Drosophila
melanogaster) 		3 / 3 TYR A   8
ARG A  53
GLN A  50
 None
SO4  A1074 (-4.0A)
None
 1.03A 1tw4A-4uutA:
undetectable		 1tw4A-4uutA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 4uut HOMEOTIC PROTEIN
ULTRABITHORAX
(Drosophila
melanogaster) 		3 / 3 TRP A  48
ARG A  52
LEU A  26
 None
None
CL  A1077 ( 4.3A)
 0.81A 5dbyA-4uutA:
undetectable		 5dbyA-4uutA:
9.09