SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uv2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 4uv2 CURLI PRODUCTION
TRANSPORT COMPONENT
CSGG
(Escherichia
coli) 		4 / 6 VAL A 224
GLY A 223
ALA A  71
LEU A  72
 None
 0.66A 1e7bB-4uv2A:
undetectable		 1e7bB-4uv2A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 4uv2 CURLI PRODUCTION
TRANSPORT COMPONENT
CSGG
(Escherichia
coli) 		4 / 5 LEU A 172
GLY A 231
ILE A  34
ILE A 121
 None
 0.84A 2q9rA-4uv2A:
undetectable		 2q9rA-4uv2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 4uv2 CURLI PRODUCTION
TRANSPORT COMPONENT
CSGG
(Escherichia
coli) 		4 / 6 LEU A  27
ASN A 229
SER A  75
PHE A  78
 None
 1.34A 3i9jB-4uv2A:
undetectable		 3i9jB-4uv2A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 4uv2 CURLI PRODUCTION
TRANSPORT COMPONENT
CSGG
(Escherichia
coli) 		4 / 5 ASP A  74
THR A  25
LEU A  24
GLU A 221
 None
 0.87A 4a3pA-4uv2A:
undetectable		 4a3pA-4uv2A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4uv2 CURLI PRODUCTION
TRANSPORT COMPONENT
CSGG
(Escherichia
coli) 		4 / 6 GLY A 231
ASP A 230
ARG A 234
GLY A 235
 None
 0.76A 5cdnR-4uv2A:
undetectable
5cdnS-4uv2A:
undetectable		 5cdnR-4uv2A:
20.97
5cdnS-4uv2A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4uv2 CURLI PRODUCTION
TRANSPORT COMPONENT
CSGG
(Escherichia
coli) 		4 / 5 SER A 183
GLU A 210
GLN A  62
ASP A 155
 None
 1.50A 5fhrB-4uv2A:
undetectable		 5fhrB-4uv2A:
21.09