SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uw7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 4uw7 L-SHAPED TAIL FIBER
PROTEIN
(Escherichia
virus
T5) 		5 / 12 LEU A1045
ASN A1018
LEU A1020
LEU A1062
THR A1105
 None
 1.18A 2aa6A-4uw7A:
undetectable		 2aa6A-4uw7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 4uw7 L-SHAPED TAIL FIBER
PROTEIN
(Escherichia
virus
T5) 		3 / 3 ARG A1078
ARG A1101
TRP A1086
 None
 1.47A 4cpzC-4uw7A:
undetectable		 4cpzC-4uw7A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4uw7 L-SHAPED TAIL FIBER
PROTEIN
(Escherichia
virus
T5) 		3 / 3 GLY A1171
SER A1172
TRP A1153
 None
 0.97A 4e7cD-4uw7A:
undetectable		 4e7cD-4uw7A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 4uw7 L-SHAPED TAIL FIBER
PROTEIN
(Escherichia
virus
T5) 		3 / 3 HIS A1043
TRP A1058
SER A1038
 None
 1.12A 4lrhD-4uw7A:
undetectable		 4lrhD-4uw7A:
20.13