SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uwa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 TRP A 147
ALA A 145
VAL A 174
 None
 0.95A 1bdwA-4uwaA:
undetectable
1bdwB-4uwaA:
undetectable		 1bdwA-4uwaA:
0.32
1bdwB-4uwaA:
0.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 LEU A 280
PHE A 316
TYR A 341
VAL A 348
 None
 0.96A 1ibgH-4uwaA:
undetectable		 1ibgH-4uwaA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 HIS A 904
HIS A 879
ASN A 921
TYR A 920
PRO A 916
 None
 1.48A 1ituA-4uwaA:
undetectable		 1ituA-4uwaA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 PHE A 133
ALA A 132
LEU A 131
SER A 124
 None
 1.02A 1sbrA-4uwaA:
undetectable
1sbrB-4uwaA:
undetectable		 1sbrA-4uwaA:
4.38
1sbrB-4uwaA:
4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 SER A1085
GLY A1086
ARG A1000
 None
 0.60A 1t9wA-4uwaA:
undetectable		 1t9wA-4uwaA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 LEU A 443
ASN A  44
ALA A  39
SER A 119
LEU A 121
 None
 1.28A 1ya3B-4uwaA:
undetectable		 1ya3B-4uwaA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 LEU A 522
LEU A 525
LEU A 484
LEU A 486
 None
 0.81A 2ab2B-4uwaA:
undetectable		 2ab2B-4uwaA:
5.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 8 SER A1171
ASP A1172
SER A1173
SER A1175
 None
 1.00A 2cmlB-4uwaA:
undetectable		 2cmlB-4uwaA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 8 SER A1171
ASP A1172
SER A1173
SER A1175
 None
 1.12A 2cmlD-4uwaA:
undetectable		 2cmlD-4uwaA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 LEU A 101
LEU A 108
LEU A 118
MET A 202
LEU A 171
 None
 1.48A 2oaxA-4uwaA:
undetectable		 2oaxA-4uwaA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 LEU A 436
PRO A 437
ARG A 493
 None
 0.64A 2qd4B-4uwaA:
undetectable		 2qd4B-4uwaA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 LEU A 526
LEU A 525
ILE A 530
ARG A 531
 None
 0.97A 2rlfA-4uwaA:
undetectable
2rlfB-4uwaA:
undetectable		 2rlfA-4uwaA:
2.65
2rlfB-4uwaA:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 LEU A 526
LEU A 525
ILE A 530
ARG A 531
 None
 0.93A 2rlfC-4uwaA:
undetectable
2rlfD-4uwaA:
undetectable		 2rlfC-4uwaA:
2.65
2rlfD-4uwaA:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 8 GLY A1129
ASN A1125
TRP A1143
ARG A1128
 None
 1.31A 3ccfA-4uwaA:
undetectable		 3ccfA-4uwaA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 ASP A 447
ARG A  45
ILE A 449
SER A 528
 None
 1.49A 3ckzA-4uwaA:
undetectable		 3ckzA-4uwaA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 ASN A 991
VAL A 995
GLY A 992
LEU A 932
GLU A 927
 None
 1.35A 3medA-4uwaA:
undetectable
3medB-4uwaA:
undetectable		 3medA-4uwaA:
8.73
3medB-4uwaA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 SER A 272
SER A 270
HIS A 218
 None
 0.84A 3mzeA-4uwaA:
undetectable		 3mzeA-4uwaA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 ARG A 871
LEU A 929
THR A 858
 None
 0.90A 3oxcA-4uwaA:
undetectable		 3oxcA-4uwaA:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 VAL A 219
PRO A  60
ILE A 205
VAL A  21
CYH A  66
 None
 1.34A 3p6gA-4uwaA:
undetectable		 3p6gA-4uwaA:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 GLN A 399
PHE A  42
TYR A 451
 None
 0.97A 3ucjB-4uwaA:
undetectable		 3ucjB-4uwaA:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 GLN A 399
PHE A  42
TYR A 451
 None
 0.94A 3ucjA-4uwaA:
undetectable		 3ucjA-4uwaA:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 LEU A 522
LEU A 525
LEU A 484
SER A 485
 None
 0.88A 3vhuA-4uwaA:
undetectable		 3vhuA-4uwaA:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 CYH A 253
THR A 254
GLY A 250
ASP A 228
 None
 1.33A 3w9tE-4uwaA:
undetectable		 3w9tE-4uwaA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 PHE A1529
LEU A1466
ILE A1516
VAL A1439
 None
 0.83A 3wrkA-4uwaA:
undetectable		 3wrkA-4uwaA:
4.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 HIS A 255
GLU A 397
ASN A 473
 None
 1.01A 4bupB-4uwaA:
undetectable		 4bupB-4uwaA:
5.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 10 ALA A 989
LEU A1039
VAL A1043
ARG A1025
ALA A 980
 None
 1.03A 4j14A-4uwaA:
undetectable		 4j14A-4uwaA:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 CYH A  36
ASN A 203
LYS A  34
 None
 1.49A 4k50A-4uwaA:
undetectable		 4k50A-4uwaA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 GLY A 409
ILE A  64
ILE A 404
LEU A 448
 None
 0.71A 4o8fB-4uwaA:
undetectable		 4o8fB-4uwaA:
5.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 MET A 403
LEU A 410
LEU A 445
LEU A 443
GLY A 450
 None
 0.95A 4pxmA-4uwaA:
undetectable		 4pxmA-4uwaA:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 TYR A1024
ARG A1036
LYS A1032
 None
 1.32A 4wq5B-4uwaA:
undetectable		 4wq5B-4uwaA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 TYR A2908
ARG A2920
LYS A2916
 None
 1.42A 4wq5B-4uwaA:
undetectable		 4wq5B-4uwaA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 11 MET A 403
LEU A 410
LEU A 445
LEU A 443
GLY A 450
 None
 0.94A 5dxgB-4uwaA:
undetectable		 5dxgB-4uwaA:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 MET A 403
LEU A 410
LEU A 445
LEU A 443
GLY A 450
 None
 0.98A 5gtrA-4uwaA:
undetectable		 5gtrA-4uwaA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 ARG A 652
ASP A 709
GLY A 708
ASP A 710
 None
 1.41A 5hp1C-4uwaA:
undetectable		 5hp1C-4uwaA:
8.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 CYH A  47
LEU A  37
HIS A 181
LEU A 180
 None
 1.04A 5hpuC-4uwaA:
undetectable
5hpuD-4uwaA:
undetectable		 5hpuC-4uwaA:
0.66
5hpuD-4uwaA:
1.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 9 LEU A 929
SER A 925
VAL A1043
LEU A1046
GLN A 981
 None
 1.30A 5o96E-4uwaA:
undetectable
5o96F-4uwaA:
undetectable		 5o96E-4uwaA:
5.22
5o96F-4uwaA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 7 LEU A2930
LYS A2928
VAL A2865
GLU A2870
 None
 1.11A 5tudA-4uwaA:
undetectable		 5tudA-4uwaA:
4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 GLU A 453
TYR A 451
ARG A 474
 None
 0.76A 5uunA-4uwaA:
undetectable		 5uunA-4uwaA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 GLU A 453
TYR A 451
ARG A 474
 None
 0.71A 5uunB-4uwaA:
undetectable		 5uunB-4uwaA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 GLY A 794
THR A 689
PRO A 779
 None
 0.51A 5v5zA-4uwaA:
undetectable		 5v5zA-4uwaA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 TYR A 103
MET A 150
THR A 149
LEU A 171
 None
 1.41A 5w97J-4uwaA:
undetectable		 5w97J-4uwaA:
1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 HIS A 255
GLU A 397
ASN A 473
 None
 0.89A 5wbvA-4uwaA:
undetectable		 5wbvA-4uwaA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 HIS A 255
GLU A 397
ASN A 473
 None
 0.90A 5wbvB-4uwaA:
undetectable		 5wbvB-4uwaA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 TYR A 103
MET A 150
THR A 149
LEU A 171
 None
 1.34A 5x1bJ-4uwaA:
undetectable		 5x1bJ-4uwaA:
1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 TYR A 103
MET A 150
THR A 149
LEU A 171
 None
 1.31A 5x1fW-4uwaA:
undetectable		 5x1fW-4uwaA:
1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 8 GLY A 734
GLN A 735
SER A 732
PHE A 768
 None
 1.02A 6eqpA-4uwaA:
undetectable		 6eqpA-4uwaA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 4uwa RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 9 LEU A2927
MET A2816
VAL A2937
LEU A2751
ILE A2823
 None
 1.37A 6fdyU-4uwaA:
undetectable		 6fdyU-4uwaA:
5.63