SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ux3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		5 / 12 LYS A1034
SER B  54
LEU A 179
LEU B  68
ILE A1030
 None
 0.98A 1lbcA-4ux3A:
undetectable
1lbcC-4ux3A:
undetectable		 1lbcA-4ux3A:
19.78
1lbcC-4ux3A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A1030
LYS A1034
SER B  54
LEU A 179
LEU B  68
 None
 1.03A 1lbcA-4ux3A:
undetectable
1lbcC-4ux3A:
undetectable		 1lbcA-4ux3A:
19.78
1lbcC-4ux3A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		4 / 8 LEU B  89
LEU A1012
ASP B  95
ARG A1015
 None
 1.11A 2j2pA-4ux3B:
undetectable
2j2pB-4ux3B:
undetectable		 2j2pA-4ux3B:
17.43
2j2pB-4ux3B:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4ux3 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		4 / 7 ILE A1206
PHE A  11
LYS A   9
TYR A  14
 None
 1.12A 3em0B-4ux3A:
undetectable		 3em0B-4ux3A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		5 / 11 LYS A1034
SER B  54
LEU A 179
LEU B  68
ILE A1030
 None
 0.96A 3h6tA-4ux3A:
undetectable
3h6tC-4ux3A:
undetectable		 3h6tA-4ux3A:
19.78
3h6tC-4ux3A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		5 / 11 ILE A1030
LYS A1034
SER B  54
LEU A 179
LEU B  68
 None
 1.03A 3h6tA-4ux3A:
undetectable
3h6tC-4ux3A:
undetectable		 3h6tA-4ux3A:
19.78
3h6tC-4ux3A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		5 / 12 LYS A1034
SER B  54
LEU A 179
LEU B  68
ILE A1030
 None
 1.03A 3iltB-4ux3A:
undetectable
3iltE-4ux3A:
undetectable		 3iltB-4ux3A:
19.14
3iltE-4ux3A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		5 / 10 ILE A1030
LYS A1034
SER B  54
LEU A 179
LEU B  68
 None
 1.11A 3iltB-4ux3A:
undetectable
3iltE-4ux3A:
undetectable		 3iltB-4ux3A:
19.14
3iltE-4ux3A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		4 / 4 ARG A 130
ASP A1146
GLY A 171
THR B  70
 None
 1.17A 3k4vB-4ux3A:
undetectable		 3k4vB-4ux3A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 4ux3 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU A1019
GLU A1018
SER A1022
ILE B  43
 None
 1.11A 4tvtA-4ux3A:
undetectable		 4tvtA-4ux3A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 4ux3 MITOTIC CHROMOSOME
DETERMINANT-RELATED
PROTEIN
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		4 / 6 LEU B  75
LYS A 173
GLU A 176
LEU A 179
 None
 1.34A 5xooA-4ux3B:
undetectable		 5xooA-4ux3B:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 4ux3 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A1156
LEU A1172
ALA A1194
LEU A1191
 None
 0.84A 5y7pE-4ux3A:
undetectable		 5y7pE-4ux3A:
21.47