SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ux5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QK8_A_MTXA200_1 (DIHYDROFOLATE REDUCTASE)	4ux5	TRANSCRIPTION FACTOR MBP1 (Magnaporthe oryzae)	5 / 12	ALA A 64 LEU A 69 ILE A 54 LEU A 101 ARG A 104	None	1.22A	2qk8A-4ux5A: undetectable	2qk8A-4ux5A: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZA_A_FOLA164_0 (DIHYDROFOLATE REDUCTASE)	4ux5	TRANSCRIPTION FACTOR MBP1 (Magnaporthe oryzae)	5 / 12	ALA A 64 LEU A 69 ILE A 54 LEU A 101 ARG A 104	None	1.19A	2zzaA-4ux5A: undetectable	2zzaA-4ux5A: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZA_B_FOLB164_0 (DIHYDROFOLATE REDUCTASE)	4ux5	TRANSCRIPTION FACTOR MBP1 (Magnaporthe oryzae)	5 / 11	ALA A 64 LEU A 69 ILE A 54 LEU A 101 ARG A 104	None	1.25A	2zzaB-4ux5A: undetectable	2zzaB-4ux5A: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G19_A_ACTA304_0 (GLUTATHIONE TRANSFERASE GTE1)	4ux5	TRANSCRIPTION FACTOR MBP1 (Magnaporthe oryzae)	4 / 5	ILE A 54 LEU A 55 LYS A 56 ASN A 50	None	1.06A	4g19A-4ux5A: undetectable	4g19A-4ux5A: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G19_D_ACTD305_0 (GLUTATHIONE TRANSFERASE GTE1)	4ux5	TRANSCRIPTION FACTOR MBP1 (Magnaporthe oryzae)	4 / 4	ILE A 54 LEU A 55 LYS A 56 ASN A 50	None	1.15A	4g19D-4ux5A: undetectable	4g19D-4ux5A: 18.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QK8_A_MTXA200_1","DIHYDROFOLATE REDUCTASE","4ux5","TRANSCRIPTION FACTOR MBP1","Magnaporthe oryzae",5,"ALA A  64;LEU A  69;ILE A  54;LEU A 101;ARG A 104","None","1.22A","2qk8A-4ux5A:undetectable","2qk8A-4ux5A:19.39"],["2ZZA_A_FOLA164_0","DIHYDROFOLATE REDUCTASE","4ux5","TRANSCRIPTION FACTOR MBP1","Magnaporthe oryzae",5,"ALA A  64;LEU A  69;ILE A  54;LEU A 101;ARG A 104","None","1.19A","2zzaA-4ux5A:undetectable","2zzaA-4ux5A:21.39"],["2ZZA_B_FOLB164_0","DIHYDROFOLATE REDUCTASE","4ux5","TRANSCRIPTION FACTOR MBP1","Magnaporthe oryzae",5,"ALA A  64;LEU A  69;ILE A  54;LEU A 101;ARG A 104","None","1.25A","2zzaB-4ux5A:undetectable","2zzaB-4ux5A:21.39"],["4G19_A_ACTA304_0","GLUTATHIONE TRANSFERASE GTE1","4ux5","TRANSCRIPTION FACTOR MBP1","Magnaporthe oryzae",4,"ILE A  54;LEU A  55;LYS A  56;ASN A  50","None","1.06A","4g19A-4ux5A:undetectable","4g19A-4ux5A:18.22"],["4G19_D_ACTD305_0","GLUTATHIONE TRANSFERASE GTE1","4ux5","TRANSCRIPTION FACTOR MBP1","Magnaporthe oryzae",4,"ILE A  54;LEU A  55;LYS A  56;ASN A  50","None","1.15A","4g19D-4ux5A:undetectable","4g19D-4ux5A:18.22"]]