SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uy6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DF7_A_MTXA501_2 (DIHYDROFOLATE REDUCTASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	3 / 3	TRP A 307 ARG A 60 THR A 68	None None TRS A1801 (-4.0A)	0.88A	1df7A-4uy6A: 2.0	1df7A-4uy6A: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EII_A_RTLA135_0 (CELLULAR RETINOL-BINDING PROTEIN II)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	ALA A 77 ILE A 164 LEU A 85 LEU A 82 LEU A 183	None	1.10A	1eiiA-4uy6A: undetectable	1eiiA-4uy6A: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWK_A_117A2_2 (HMG-COA REDUCTASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 11	GLU A 295 SER A 317 LEU A 191 ALA A 319 LEU A 189	None	1.08A	1hwkB-4uy6A: undetectable	1hwkB-4uy6A: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWK_B_117B1_1 (HMG-COA REDUCTASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 11	GLU A 295 SER A 317 LEU A 191 ALA A 319 LEU A 189	None	1.11A	1hwkA-4uy6A: undetectable	1hwkA-4uy6A: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWK_C_117C4_2 (HMG-COA REDUCTASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 11	GLU A 295 SER A 317 LEU A 191 ALA A 319 LEU A 189	None	1.09A	1hwkD-4uy6A: undetectable	1hwkD-4uy6A: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWK_D_117D3_1 (HMG-COA REDUCTASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 11	GLU A 295 SER A 317 LEU A 191 ALA A 319 LEU A 189	None	1.08A	1hwkC-4uy6A: undetectable	1hwkC-4uy6A: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QAO_A_SAMA245_0 (ERMC' METHYLTRANSFERASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLU A 84 GLY A 86 GLY A 88 ASP A 115 ASP A 141	SAH A 801 ( 4.6A) SAH A 801 (-3.0A) SAH A 801 (-3.2A) None SAH A 801 (-3.7A)	0.64A	1qaoA-4uy6A: 9.1	1qaoA-4uy6A: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_B_CHDB1130_0 (FATTY ACID-BINDING PROTEIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 183 LEU A 296 ILE A 164 ILE A 149 LEU A 146	None	1.03A	1tw4B-4uy6A: undetectable	1tw4B-4uy6A: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_1 (RETINOIC ACID RECEPTOR, BETA)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	ALA A 76 LEU A 190 LEU A 318 LEU A 66 LEU A 156	None	1.01A	1xdkB-4uy6A: undetectable	1xdkB-4uy6A: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_1 (RETINOIC ACID RECEPTOR, BETA)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	ALA A 76 LEU A 190 LEU A 318 LEU A 66 LEU A 156	None	1.02A	1xdkF-4uy6A: undetectable	1xdkF-4uy6A: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XWF_A_ADNA433_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 ASP A 141 LEU A 85 GLY A 86	None SAH A 801 ( 3.7A) SAH A 801 (-3.7A) None SAH A 801 (-3.0A)	1.19A	1xwfA-4uy6A: 4.4	1xwfA-4uy6A: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XWF_B_ADNB433_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 ASP A 141 LEU A 85 GLY A 86	None SAH A 801 ( 3.7A) SAH A 801 (-3.7A) None SAH A 801 (-3.0A)	1.17A	1xwfB-4uy6A: 4.4	1xwfB-4uy6A: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XWF_C_ADNC433_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 ASP A 141 LEU A 85 GLY A 86	None SAH A 801 ( 3.7A) SAH A 801 (-3.7A) None SAH A 801 (-3.0A)	1.19A	1xwfC-4uy6A: 2.7	1xwfC-4uy6A: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AW1_A_COXA264_1 (CARBONIC ANHYDRASE II)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	HIS A 151 VAL A 157 LEU A 85 VAL A 83 LEU A 146	None	0.96A	2aw1A-4uy6A: undetectable	2aw1A-4uy6A: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F8L_A_SAMA400_1 (HYPOTHETICAL PROTEIN LMO1582)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	4 / 4	THR A 93 THR A 89 ASP A 113 ASP A 141	None None SAH A 801 (-3.0A) SAH A 801 (-3.7A)	1.29A	2f8lA-4uy6A: 11.2	2f8lA-4uy6A: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GEH_A_NHYA300_1 (CARBONIC ANHYDRASE 2)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	4 / 8	HIS A 151 VAL A 157 VAL A 83 LEU A 146	None	0.87A	2gehA-4uy6A: undetectable	2gehA-4uy6A: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OKC_A_SAMA500_1 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	4 / 6	THR A 93 THR A 89 ASP A 113 ASP A 141	None None SAH A 801 (-3.0A) SAH A 801 (-3.7A)	1.19A	2okcA-4uy6A: 9.2	2okcA-4uy6A: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OKC_B_SAMB500_1 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	4 / 6	THR A 93 ARG A 94 ASP A 113 ASP A 141	None None SAH A 801 (-3.0A) SAH A 801 (-3.7A)	0.99A	2okcB-4uy6A: 9.2	2okcB-4uy6A: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OKC_B_SAMB500_1 (TYPE I RESTRICTION ENZYME STYSJI M PROTEIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	4 / 6	THR A 93 THR A 89 ASP A 113 ASP A 141	None None SAH A 801 (-3.0A) SAH A 801 (-3.7A)	1.21A	2okcB-4uy6A: 9.2	2okcB-4uy6A: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_A_2FAA500_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.40A	2zj0A-4uy6A: 4.6	2zj0A-4uy6A: 22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_A_ADNA500_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.37A	3ce6A-4uy6A: 3.5	3ce6A-4uy6A: 22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DXY_A_SAMA1_0 (TRNA (GUANINE-N(7)-)-METH YLTRANSFERASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 11	GLU A 84 GLY A 86 GLY A 88 VAL A 114 ASP A 141	SAH A 801 ( 4.6A) SAH A 801 (-3.0A) SAH A 801 (-3.2A) SAH A 801 (-4.1A) SAH A 801 (-3.7A)	0.60A	3dxyA-4uy6A: 10.9	3dxyA-4uy6A: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_C_ADNC438_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.08A	3g1uC-4uy6A: 4.3	3g1uC-4uy6A: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LP9_D_SPMD230_1 (LS-24)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	3 / 3	GLU A 248 GLU A 295 ASN A 291	None	0.89A	3lp9B-4uy6A: undetectable 3lp9D-4uy6A: undetectable	3lp9B-4uy6A: 22.22 3lp9D-4uy6A: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_C_SAMC300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	3 / 3	GLY A 88 ASP A 113 ASP A 141	SAH A 801 (-3.2A) SAH A 801 (-3.0A) SAH A 801 (-3.7A)	0.30A	3ou7C-4uy6A: 15.4	3ou7C-4uy6A: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PRS_A_RITA1001_2 (ENDOTHIAPEPSIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	ASP A 45 ASP A 115 ASP A 113 GLY A 86 PHE A 159	None None SAH A 801 (-3.0A) SAH A 801 (-3.0A) None	1.13A	3prsA-4uy6A: undetectable	3prsA-4uy6A: 23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SGL_A_SAMA692_0 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLU A 84 GLY A 86 GLY A 88 THR A 89 ASP A 141	SAH A 801 ( 4.6A) SAH A 801 (-3.0A) SAH A 801 (-3.2A) None SAH A 801 (-3.7A)	0.63A	3sglA-4uy6A: 7.7	3sglA-4uy6A: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SM2_A_478A126_2 (GAG-PRO-POL POLYPROTEIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 11	VAL A 224 GLY A 25 ALA A 24 LEU A 221 LEU A 228	None	0.99A	3sm2B-4uy6A: undetectable	3sm2B-4uy6A: 16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W68_A_VIVA301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 267 PHE A 273 VAL A 22 LEU A 33 VAL A 220	None	1.20A	3w68A-4uy6A: undetectable	3w68A-4uy6A: 23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I13_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	3 / 3	ASP A 48 ARG A 60 THR A 89	None	0.66A	4i13A-4uy6A: 2.9	4i13A-4uy6A: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K13_A_ETSA304_1 (CARBONIC ANHYDRASE 2)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	HIS A 151 VAL A 157 LEU A 85 VAL A 83 LEU A 146	None	0.99A	4k13A-4uy6A: undetectable	4k13A-4uy6A: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LVC_A_ADNA501_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE (SAHASE))	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.12A	4lvcA-4uy6A: 2.2	4lvcA-4uy6A: 24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LVC_C_ADNC501_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE (SAHASE))	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.07A	4lvcC-4uy6A: 4.6	4lvcC-4uy6A: 24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2V_A_BZ1A302_1 (CARBONIC ANHYDRASE 2)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 189 HIS A 151 VAL A 157 VAL A 83 LEU A 146	None	0.97A	4m2vA-4uy6A: undetectable	4m2vA-4uy6A: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2W_A_ETSA302_1 (CARBONIC ANHYDRASE 2)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	6 / 12	LEU A 189 HIS A 151 VAL A 157 LEU A 85 VAL A 83 LEU A 146	None	1.08A	4m2wA-4uy6A: undetectable	4m2wA-4uy6A: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P3R_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	3 / 3	ASP A 48 ARG A 60 THR A 89	None	0.67A	4p3rA-4uy6A: 2.0	4p3rA-4uy6A: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.08A	4pfjA-4uy6A: 4.1	4pfjA-4uy6A: 22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_A_GCSA303_1 (CHITOSANASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	4 / 6	GLU A 282 TYR A 206 ILE A 50 THR A 213	HIS A 800 (-3.0A) HIS A 800 (-4.4A) HIS A 800 ( 4.2A) HIS A 800 ( 4.5A)	1.43A	4qwpA-4uy6A: undetectable	4qwpA-4uy6A: 25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_B_GCSB302_1 (CHITOSANASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	4 / 5	GLU A 282 TYR A 206 ILE A 50 THR A 213	HIS A 800 (-3.0A) HIS A 800 (-4.4A) HIS A 800 ( 4.2A) HIS A 800 ( 4.5A)	1.44A	4qwpB-4uy6A: undetectable	4qwpB-4uy6A: 25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE1_A_X2NA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 25 LEU A 167 PHE A 159 PHE A 142 GLY A 86	None None None SAH A 801 (-3.4A) SAH A 801 (-3.0A)	1.04A	4ze1A-4uy6A: undetectable	4ze1A-4uy6A: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE2_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 25 LEU A 167 PHE A 159 PHE A 142 GLY A 86	None None None SAH A 801 (-3.4A) SAH A 801 (-3.0A)	1.10A	4ze2A-4uy6A: undetectable	4ze2A-4uy6A: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXA_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.08A	5axaA-4uy6A: 4.2	5axaA-4uy6A: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXA_C_ADNC502_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.08A	5axaC-4uy6A: 4.3	5axaC-4uy6A: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_A_SAMA301_0 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 86 GLY A 88 THR A 93 ASP A 113 LEU A 160	SAH A 801 (-3.0A) SAH A 801 (-3.2A) None SAH A 801 (-3.0A) SAH A 801 ( 4.9A)	0.96A	5bw4A-4uy6A: 10.3	5bw4A-4uy6A: 22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESK_A_1YNA701_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 25 LEU A 167 PHE A 159 PHE A 142 GLY A 86	None None None SAH A 801 (-3.4A) SAH A 801 (-3.0A)	1.06A	5eskA-4uy6A: undetectable	5eskA-4uy6A: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FSA_A_X2NA590_1 (CYP51 VARIANT1)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	ALA A 24 LEU A 167 PHE A 159 PHE A 142 GLY A 86	None None None SAH A 801 (-3.4A) SAH A 801 (-3.0A)	1.21A	5fsaA-4uy6A: 2.1	5fsaA-4uy6A: 21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FSA_B_X2NB590_1 (CYP51 VARIANT1)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 25 LEU A 167 PHE A 159 PHE A 142 GLY A 86	None None None SAH A 801 (-3.4A) SAH A 801 (-3.0A)	1.01A	5fsaB-4uy6A: undetectable	5fsaB-4uy6A: 21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.07A	5m5kA-4uy6A: 4.5	5m5kA-4uy6A: 24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_B_ADNB502_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.08A	5m5kB-4uy6A: 4.4	5m5kB-4uy6A: 24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_B_ADNB502_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.06A	5m66B-4uy6A: 4.2	5m66B-4uy6A: 24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O96_H_SAMH501_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 10	GLY A 153 VAL A 157 LEU A 156 THR A 81 ALA A 79	None	0.76A	5o96G-4uy6A: undetectable 5o96H-4uy6A: 3.7	5o96G-4uy6A: 21.01 5o96H-4uy6A: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_A_ADNA502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.03A	5v96A-4uy6A: 2.6	5v96A-4uy6A: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_B_ADNB502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.04A	5v96B-4uy6A: 2.3	5v96B-4uy6A: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_C_ADNC502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.04A	5v96C-4uy6A: 2.6	5v96C-4uy6A: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V96_D_ADND502_1 (S-ADENOSYL-L-HOMOCYS TEINE HYDROLASE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.03A	5v96D-4uy6A: 2.6	5v96D-4uy6A: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6APH_A_ADNA501_1 (ADENOSYLHOMOCYSTEINA SE)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.09A	6aphA-4uy6A: 4.4	6aphA-4uy6A: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_A_ADNA401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 86 ASP A 113 ASP A 115 VAL A 118 ASP A 141	SAH A 801 (-3.0A) SAH A 801 (-3.0A) None None SAH A 801 (-3.7A)	0.75A	6bq4A-4uy6A: 10.8	6bq4A-4uy6A: 12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_B_ADNB401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 86 ASP A 113 ASP A 115 VAL A 118 ASP A 141	SAH A 801 (-3.0A) SAH A 801 (-3.0A) None None SAH A 801 (-3.7A)	0.69A	6bq4B-4uy6A: 10.8	6bq4B-4uy6A: 12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_A_ADNA501_1 (-)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.08A	6gbnA-4uy6A: 3.4	6gbnA-4uy6A: 24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_B_ADNB501_1 (-)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.08A	6gbnB-4uy6A: 3.2	6gbnB-4uy6A: 24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_D_ADND501_1 (-)	4uy6	HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD (Mycolicibacteriu m smegmatis)	5 / 12	LEU A 167 THR A 163 GLU A 143 ASP A 141 GLY A 86	None SAH A 801 ( 3.7A) None SAH A 801 (-3.7A) SAH A 801 (-3.0A)	1.08A	6gbnD-4uy6A: 3.2	6gbnD-4uy6A: 24.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DF7_A_MTXA501_2","DIHYDROFOLATE REDUCTASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",3,"TRP A 307;ARG A  60;THR A  68","None;None;TRS A1801 (-4.0A)","0.88A","1df7A-4uy6A:2.0","1df7A-4uy6A:21.05"],["1EII_A_RTLA135_0","CELLULAR RETINOL-BINDING PROTEIN II","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"ALA A  77;ILE A 164;LEU A  85;LEU A  82;LEU A 183","None","1.10A","1eiiA-4uy6A:undetectable","1eiiA-4uy6A:17.72"],["1HWK_A_117A2_2","HMG-COA REDUCTASE;HMG-COA REDUCTASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLU A 295;SER A 317;LEU A 191;ALA A 319;LEU A 189","None","1.08A","1hwkB-4uy6A:undetectable","1hwkB-4uy6A:21.53"],["1HWK_B_117B1_1","HMG-COA REDUCTASE;HMG-COA REDUCTASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLU A 295;SER A 317;LEU A 191;ALA A 319;LEU A 189","None","1.11A","1hwkA-4uy6A:undetectable","1hwkA-4uy6A:21.53"],["1HWK_C_117C4_2","HMG-COA REDUCTASE;HMG-COA REDUCTASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLU A 295;SER A 317;LEU A 191;ALA A 319;LEU A 189","None","1.09A","1hwkD-4uy6A:undetectable","1hwkD-4uy6A:21.53"],["1HWK_D_117D3_1","HMG-COA REDUCTASE;HMG-COA REDUCTASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLU A 295;SER A 317;LEU A 191;ALA A 319;LEU A 189","None","1.08A","1hwkC-4uy6A:undetectable","1hwkC-4uy6A:21.53"],["1QAO_A_SAMA245_0","ERMC' METHYLTRANSFERASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLU A  84;GLY A  86;GLY A  88;ASP A 115;ASP A 141","SAH A 801 ( 4.6A);SAH A 801 (-3.0A);SAH A 801 (-3.2A);None;SAH A 801 (-3.7A)","0.64A","1qaoA-4uy6A:9.1","1qaoA-4uy6A:20.47"],["1TW4_B_CHDB1130_0","FATTY ACID-BINDING PROTEIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 183;LEU A 296;ILE A 164;ILE A 149;LEU A 146","None","1.03A","1tw4B-4uy6A:undetectable","1tw4B-4uy6A:18.15"],["1XDK_B_9CRB600_1","RETINOIC ACID RECEPTOR, BETA","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"ALA A  76;LEU A 190;LEU A 318;LEU A  66;LEU A 156","None","1.01A","1xdkB-4uy6A:undetectable","1xdkB-4uy6A:22.79"],["1XDK_F_9CRF1600_1","RETINOIC ACID RECEPTOR, BETA","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"ALA A  76;LEU A 190;LEU A 318;LEU A  66;LEU A 156","None","1.02A","1xdkF-4uy6A:undetectable","1xdkF-4uy6A:22.79"],["1XWF_A_ADNA433_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;ASP A 141;LEU A  85;GLY A  86","None;SAH A 801 ( 3.7A);SAH A 801 (-3.7A);None;SAH A 801 (-3.0A)","1.19A","1xwfA-4uy6A:4.4","1xwfA-4uy6A:22.58"],["1XWF_B_ADNB433_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;ASP A 141;LEU A  85;GLY A  86","None;SAH A 801 ( 3.7A);SAH A 801 (-3.7A);None;SAH A 801 (-3.0A)","1.17A","1xwfB-4uy6A:4.4","1xwfB-4uy6A:22.58"],["1XWF_C_ADNC433_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;ASP A 141;LEU A  85;GLY A  86","None;SAH A 801 ( 3.7A);SAH A 801 (-3.7A);None;SAH A 801 (-3.0A)","1.19A","1xwfC-4uy6A:2.7","1xwfC-4uy6A:22.58"],["2AW1_A_COXA264_1","CARBONIC ANHYDRASE II","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"HIS A 151;VAL A 157;LEU A  85;VAL A  83;LEU A 146","None","0.96A","2aw1A-4uy6A:undetectable","2aw1A-4uy6A:20.30"],["2F8L_A_SAMA400_1","HYPOTHETICAL PROTEIN LMO1582","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",4,"THR A  93;THR A  89;ASP A 113;ASP A 141","None;None;SAH A 801 (-3.0A);SAH A 801 (-3.7A)","1.29A","2f8lA-4uy6A:11.2","2f8lA-4uy6A:23.45"],["2GEH_A_NHYA300_1","CARBONIC ANHYDRASE 2","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",4,"HIS A 151;VAL A 157;VAL A  83;LEU A 146","None","0.87A","2gehA-4uy6A:undetectable","2gehA-4uy6A:20.30"],["2OKC_A_SAMA500_1","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",4,"THR A  93;THR A  89;ASP A 113;ASP A 141","None;None;SAH A 801 (-3.0A);SAH A 801 (-3.7A)","1.19A","2okcA-4uy6A:9.2","2okcA-4uy6A:22.80"],["2OKC_B_SAMB500_1","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",4,"THR A  93;ARG A  94;ASP A 113;ASP A 141","None;None;SAH A 801 (-3.0A);SAH A 801 (-3.7A)","0.99A","2okcB-4uy6A:9.2","2okcB-4uy6A:22.80"],["2OKC_B_SAMB500_1","TYPE I RESTRICTION ENZYME STYSJI M PROTEIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",4,"THR A  93;THR A  89;ASP A 113;ASP A 141","None;None;SAH A 801 (-3.0A);SAH A 801 (-3.7A)","1.21A","2okcB-4uy6A:9.2","2okcB-4uy6A:22.80"],["2ZJ0_A_2FAA500_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.40A","2zj0A-4uy6A:4.6","2zj0A-4uy6A:22.55"],["3CE6_A_ADNA500_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.37A","3ce6A-4uy6A:3.5","3ce6A-4uy6A:22.55"],["3DXY_A_SAMA1_0","TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLU A  84;GLY A  86;GLY A  88;VAL A 114;ASP A 141","SAH A 801 ( 4.6A);SAH A 801 (-3.0A);SAH A 801 (-3.2A);SAH A 801 (-4.1A);SAH A 801 (-3.7A)","0.60A","3dxyA-4uy6A:10.9","3dxyA-4uy6A:20.43"],["3G1U_C_ADNC438_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.08A","3g1uC-4uy6A:4.3","3g1uC-4uy6A:22.91"],["3LP9_D_SPMD230_1","LS-24;LS-24","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",3,"GLU A 248;GLU A 295;ASN A 291","None","0.89A","3lp9B-4uy6A:undetectable;3lp9D-4uy6A:undetectable","3lp9B-4uy6A:22.22;3lp9D-4uy6A:22.22"],["3OU7_C_SAMC300_1","SAM-DEPENDENT METHYLTRANSFERASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",3,"GLY A  88;ASP A 113;ASP A 141","SAH A 801 (-3.2A);SAH A 801 (-3.0A);SAH A 801 (-3.7A)","0.30A","3ou7C-4uy6A:15.4","3ou7C-4uy6A:23.87"],["3PRS_A_RITA1001_2","ENDOTHIAPEPSIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"ASP A  45;ASP A 115;ASP A 113;GLY A  86;PHE A 159","None;None;SAH A 801 (-3.0A);SAH A 801 (-3.0A);None","1.13A","3prsA-4uy6A:undetectable","3prsA-4uy6A:23.67"],["3SGL_A_SAMA692_0","TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLU A  84;GLY A  86;GLY A  88;THR A  89;ASP A 141","SAH A 801 ( 4.6A);SAH A 801 (-3.0A);SAH A 801 (-3.2A);None;SAH A 801 (-3.7A)","0.63A","3sglA-4uy6A:7.7","3sglA-4uy6A:20.58"],["3SM2_A_478A126_2","GAG-PRO-POL POLYPROTEIN;GAG-PRO-POL POLYPROTEIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"VAL A 224;GLY A  25;ALA A  24;LEU A 221;LEU A 228","None","0.99A","3sm2B-4uy6A:undetectable","3sm2B-4uy6A:16.20"],["3W68_A_VIVA301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 267;PHE A 273;VAL A  22;LEU A  33;VAL A 220","None","1.20A","3w68A-4uy6A:undetectable","3w68A-4uy6A:23.74"],["4I13_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",3,"ASP A  48;ARG A  60;THR A  89","None","0.66A","4i13A-4uy6A:2.9","4i13A-4uy6A:19.44"],["4K13_A_ETSA304_1","CARBONIC ANHYDRASE 2","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"HIS A 151;VAL A 157;LEU A  85;VAL A  83;LEU A 146","None","0.99A","4k13A-4uy6A:undetectable","4k13A-4uy6A:20.77"],["4LVC_A_ADNA501_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (SAHASE)","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.12A","4lvcA-4uy6A:2.2","4lvcA-4uy6A:24.22"],["4LVC_C_ADNC501_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (SAHASE)","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.07A","4lvcC-4uy6A:4.6","4lvcC-4uy6A:24.22"],["4M2V_A_BZ1A302_1","CARBONIC ANHYDRASE 2","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 189;HIS A 151;VAL A 157;VAL A  83;LEU A 146","None","0.97A","4m2vA-4uy6A:undetectable","4m2vA-4uy6A:20.88"],["4M2W_A_ETSA302_1","CARBONIC ANHYDRASE 2","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",6,"LEU A 189;HIS A 151;VAL A 157;LEU A  85;VAL A  83;LEU A 146","None","1.08A","4m2wA-4uy6A:undetectable","4m2wA-4uy6A:20.77"],["4P3R_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",3,"ASP A  48;ARG A  60;THR A  89","None","0.67A","4p3rA-4uy6A:2.0","4p3rA-4uy6A:19.44"],["4PFJ_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.08A","4pfjA-4uy6A:4.1","4pfjA-4uy6A:22.88"],["4QWP_A_GCSA303_1","CHITOSANASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",4,"GLU A 282;TYR A 206;ILE A  50;THR A 213","HIS A 800 (-3.0A);HIS A 800 (-4.4A);HIS A 800 ( 4.2A);HIS A 800 ( 4.5A)","1.43A","4qwpA-4uy6A:undetectable","4qwpA-4uy6A:25.21"],["4QWP_B_GCSB302_1","CHITOSANASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",4,"GLU A 282;TYR A 206;ILE A  50;THR A 213","HIS A 800 (-3.0A);HIS A 800 (-4.4A);HIS A 800 ( 4.2A);HIS A 800 ( 4.5A)","1.44A","4qwpB-4uy6A:undetectable","4qwpB-4uy6A:25.21"],["4ZE1_A_X2NA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLY A  25;LEU A 167;PHE A 159;PHE A 142;GLY A  86","None;None;None;SAH A 801 (-3.4A);SAH A 801 (-3.0A)","1.04A","4ze1A-4uy6A:undetectable","4ze1A-4uy6A:19.59"],["4ZE2_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLY A  25;LEU A 167;PHE A 159;PHE A 142;GLY A  86","None;None;None;SAH A 801 (-3.4A);SAH A 801 (-3.0A)","1.10A","4ze2A-4uy6A:undetectable","4ze2A-4uy6A:19.59"],["5AXA_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.08A","5axaA-4uy6A:4.2","5axaA-4uy6A:21.75"],["5AXA_C_ADNC502_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.08A","5axaC-4uy6A:4.3","5axaC-4uy6A:21.75"],["5BW4_A_SAMA301_0","16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLY A  86;GLY A  88;THR A  93;ASP A 113;LEU A 160","SAH A 801 (-3.0A);SAH A 801 (-3.2A);None;SAH A 801 (-3.0A);SAH A 801 ( 4.9A)","0.96A","5bw4A-4uy6A:10.3","5bw4A-4uy6A:22.89"],["5ESK_A_1YNA701_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLY A  25;LEU A 167;PHE A 159;PHE A 142;GLY A  86","None;None;None;SAH A 801 (-3.4A);SAH A 801 (-3.0A)","1.06A","5eskA-4uy6A:undetectable","5eskA-4uy6A:19.59"],["5FSA_A_X2NA590_1","CYP51 VARIANT1","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"ALA A  24;LEU A 167;PHE A 159;PHE A 142;GLY A  86","None;None;None;SAH A 801 (-3.4A);SAH A 801 (-3.0A)","1.21A","5fsaA-4uy6A:2.1","5fsaA-4uy6A:21.24"],["5FSA_B_X2NB590_1","CYP51 VARIANT1","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLY A  25;LEU A 167;PHE A 159;PHE A 142;GLY A  86","None;None;None;SAH A 801 (-3.4A);SAH A 801 (-3.0A)","1.01A","5fsaB-4uy6A:undetectable","5fsaB-4uy6A:21.24"],["5M5K_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.07A","5m5kA-4uy6A:4.5","5m5kA-4uy6A:24.22"],["5M5K_B_ADNB502_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.08A","5m5kB-4uy6A:4.4","5m5kB-4uy6A:24.22"],["5M66_B_ADNB502_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.06A","5m66B-4uy6A:4.2","5m66B-4uy6A:24.22"],["5O96_H_SAMH501_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLY A 153;VAL A 157;LEU A 156;THR A  81;ALA A  79","None","0.76A","5o96G-4uy6A:undetectable;5o96H-4uy6A:3.7","5o96G-4uy6A:21.01;5o96H-4uy6A:21.01"],["5V96_A_ADNA502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.03A","5v96A-4uy6A:2.6","5v96A-4uy6A:22.92"],["5V96_B_ADNB502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.04A","5v96B-4uy6A:2.3","5v96B-4uy6A:22.92"],["5V96_C_ADNC502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.04A","5v96C-4uy6A:2.6","5v96C-4uy6A:22.92"],["5V96_D_ADND502_1","S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.03A","5v96D-4uy6A:2.6","5v96D-4uy6A:22.92"],["6APH_A_ADNA501_1","ADENOSYLHOMOCYSTEINASE","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.09A","6aphA-4uy6A:4.4","6aphA-4uy6A:22.12"],["6BQ4_A_ADNA401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLY A  86;ASP A 113;ASP A 115;VAL A 118;ASP A 141","SAH A 801 (-3.0A);SAH A 801 (-3.0A);None;None;SAH A 801 (-3.7A)","0.75A","6bq4A-4uy6A:10.8","6bq4A-4uy6A:12.34"],["6BQ4_B_ADNB401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"GLY A  86;ASP A 113;ASP A 115;VAL A 118;ASP A 141","SAH A 801 (-3.0A);SAH A 801 (-3.0A);None;None;SAH A 801 (-3.7A)","0.69A","6bq4B-4uy6A:10.8","6bq4B-4uy6A:12.34"],["6GBN_A_ADNA501_1","-","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.08A","6gbnA-4uy6A:3.4","6gbnA-4uy6A:24.23"],["6GBN_B_ADNB501_1","-","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.08A","6gbnB-4uy6A:3.2","6gbnB-4uy6A:24.23"],["6GBN_D_ADND501_1","-","4uy6","HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD","Mycolicibacterium smegmatis",5,"LEU A 167;THR A 163;GLU A 143;ASP A 141;GLY A  86","None;SAH A 801 ( 3.7A);None;SAH A 801 (-3.7A);SAH A 801 (-3.0A)","1.08A","6gbnD-4uy6A:3.2","6gbnD-4uy6A:24.23"]]