SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uyi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4uyi STRUCTURE-SPECIFIC
ENDONUCLEASE SUBUNIT
SLX4
(Homo
sapiens) 		5 / 12 PHE A 695
SER A 691
LEU A 752
LEU A 710
TYR A 756
 None
 1.21A 4xumA-4uyiA:
undetectable		 4xumA-4uyiA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4uyi STRUCTURE-SPECIFIC
ENDONUCLEASE SUBUNIT
SLX4
(Homo
sapiens) 		5 / 11 GLY A 741
SER A 771
LEU A 770
THR A 745
ALA A 747
 None
 1.12A 5o96A-4uyiA:
undetectable
5o96B-4uyiA:
undetectable		 5o96A-4uyiA:
21.85
5o96B-4uyiA:
21.85