SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 6 PHE A 486
LEU A 333
VAL A 362
VAL A 320
 None
 0.70A 1e7aB-4uymA:
undetectable		 1e7aB-4uymA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		3 / 3 ASP A 435
GLU A 466
TYR A 442
 None
 0.67A 1wsvA-4uymA:
undetectable		 1wsvA-4uymA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 SER A 283
PHE A 149
VAL A 134
ALA A 303
ASP A 276
 None
None
None
VOR  A 590 ( 4.4A)
None
 1.25A 2avdB-4uymA:
undetectable		 2avdB-4uymA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 7 SER A  64
THR A  96
HIS A 397
GLY A  93
 None
 1.05A 2ddwB-4uymA:
undetectable		 2ddwB-4uymA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 6 PHE A  87
ILE A  86
GLY A 101
GLY A 104
 None
 0.80A 2qx6A-4uymA:
undetectable
2qx6B-4uymA:
undetectable		 2qx6A-4uymA:
20.58
2qx6B-4uymA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 6 GLU A 466
TYR A 470
PHE A 456
PRO A 455
 None
None
HEM  A 580 (-4.5A)
None
 1.45A 2vmyA-4uymA:
undetectable		 2vmyA-4uymA:
23.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 7 PHE A 130
TYR A 136
ALA A 303
ALA A 307
 VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
 0.55A 2wx2A-4uymA:
40.0		 2wx2A-4uymA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 8 TYR A 122
PHE A 130
TYR A 136
ALA A 303
ALA A 307
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
 0.58A 2wx2B-4uymA:
38.1		 2wx2B-4uymA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 ILE A  62
TYR A 122
TYR A 136
ALA A 303
ALA A 307
 None
VOR  A 590 (-3.8A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
 1.18A 2x2nD-4uymA:
36.8		 2x2nD-4uymA:
32.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 9 TYR A  73
PHE A  76
VAL A 405
GLY A 404
ILE A 376
 None
None
None
None
HEM  A 580 (-4.2A)
 1.44A 3csjB-4uymA:
undetectable		 3csjB-4uymA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 5 LEU A 358
GLN A 335
LEU A 333
GLU A 332
 None
 1.11A 3h5gA-4uymA:
undetectable
3h5gB-4uymA:
undetectable		 3h5gA-4uymA:
5.85
3h5gB-4uymA:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		3 / 3 ARG A 160
ASP A 273
ASP A 157
 None
 0.65A 3jayA-4uymA:
undetectable		 3jayA-4uymA:
18.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 8 TYR A 122
LEU A 125
TYR A 136
ILE A 373
 VOR  A 590 (-3.8A)
None
HEM  A 580 (-4.6A)
HEM  A 580 (-4.1A)
 0.72A 3jusA-4uymA:
48.0		 3jusA-4uymA:
39.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 8 TYR A 122
THR A 126
TYR A 136
ALA A 307
ILE A 373
 VOR  A 590 (-3.8A)
None
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.0A)
HEM  A 580 (-4.1A)
 0.77A 3jusA-4uymA:
48.0		 3jusA-4uymA:
39.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 8 TYR A 122
LEU A 125
TYR A 136
ILE A 373
 VOR  A 590 (-3.8A)
None
HEM  A 580 (-4.6A)
HEM  A 580 (-4.1A)
 0.72A 3jusA-4uymA:
48.0		 3jusA-4uymA:
39.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 8 TYR A 122
THR A 126
TYR A 136
ALA A 307
ILE A 373
 VOR  A 590 (-3.8A)
None
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.0A)
HEM  A 580 (-4.1A)
 0.77A 3jusA-4uymA:
48.0		 3jusA-4uymA:
39.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 9 TYR A 122
LEU A 125
THR A 126
TYR A 136
ALA A 307
ILE A 373
 VOR  A 590 (-3.8A)
None
None
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.0A)
HEM  A 580 (-4.1A)
 0.86A 3jusB-4uymA:
47.9		 3jusB-4uymA:
39.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 8 TYR A 122
PHE A 130
TYR A 136
ALA A 303
ALA A 307
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
 0.65A 3khmA-4uymA:
41.4		 3khmA-4uymA:
31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 8 TYR A 122
TYR A 136
ALA A 303
ALA A 307
 VOR  A 590 (-3.8A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
 0.69A 3l4dA-4uymA:
41.4		 3l4dA-4uymA:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4D_C_TPFC490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 9 TYR A 122
PHE A 130
TYR A 136
ALA A 303
ALA A 307
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
 0.98A 3l4dC-4uymA:
36.4		 3l4dC-4uymA:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 12 TYR A 122
PHE A 130
TYR A 136
PHE A 229
ALA A 307
ILE A 373
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
VOR  A 590 ( 4.0A)
HEM  A 580 (-4.1A)
 0.82A 3ld6A-4uymA:
48.4		 3ld6A-4uymA:
39.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 TYR A 122
PHE A 130
TYR A 136
ALA A 307
ILE A 373
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.0A)
HEM  A 580 (-4.1A)
 0.71A 3ld6B-4uymA:
48.1		 3ld6B-4uymA:
39.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 TYR A 122
PHE A 130
TYR A 136
PHE A 229
ALA A 307
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
VOR  A 590 ( 4.0A)
 0.70A 3ld6B-4uymA:
48.1		 3ld6B-4uymA:
39.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 12 LEU A 417
ALA A  81
LYS A  74
TYR A  73
HIS A 370
ARG A 368
 None
 1.35A 4l9qA-4uymA:
undetectable		 4l9qA-4uymA:
21.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 GLY A  69
LEU A 125
PHE A 130
PHE A 229
HIS A 374
 None
None
VOR  A 590 (-4.6A)
None
None
 1.17A 4ze1A-4uymA:
52.3		 4ze1A-4uymA:
50.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 TYR A  68
GLY A  69
LEU A 125
PHE A 130
HIS A 374
 None
None
None
VOR  A 590 (-4.6A)
None
 0.98A 4ze1A-4uymA:
52.3		 4ze1A-4uymA:
50.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 12 GLY A  69
TYR A 122
LEU A 125
PHE A 130
PHE A 229
HIS A 374
 None
VOR  A 590 (-3.8A)
None
VOR  A 590 (-4.6A)
None
None
 1.16A 4ze2A-4uymA:
52.3		 4ze2A-4uymA:
50.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 GLY A  69
PHE A 130
TYR A 136
PHE A 229
HIS A 374
 None
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
None
 0.97A 5eqbA-4uymA:
52.5		 5eqbA-4uymA:
50.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 TYR A  68
PHE A 130
TYR A 136
PHE A 229
HIS A 374
 None
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
None
 0.98A 5esgA-4uymA:
52.5		 5esgA-4uymA:
50.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 12 GLY A  69
TYR A 122
LEU A 125
PHE A 130
TYR A 136
PHE A 229
 None
VOR  A 590 (-3.8A)
None
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
 1.19A 5eskA-4uymA:
51.9		 5eskA-4uymA:
45.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 12 GLY A  69
TYR A 122
PHE A 130
TYR A 136
PHE A 229
HIS A 374
 None
VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
None
 1.07A 5eslA-4uymA:
51.4		 5eslA-4uymA:
50.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 125
PHE A 130
TYR A 136
PHE A 229
HIS A 374
 None
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
None
 1.20A 5fsaB-4uymA:
51.5		 5fsaB-4uymA:
50.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 12 TYR A  68
GLY A  69
LEU A 125
PHE A 130
TYR A 136
HIS A 374
 None
None
None
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
 1.01A 5fsaB-4uymA:
51.5		 5fsaB-4uymA:
50.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 6 ILE A 428
ALA A 430
ILE A 363
TYR A 453
 None
 0.83A 5mvmB-4uymA:
undetectable
5mvmC-4uymA:
undetectable		 5mvmB-4uymA:
10.24
5mvmC-4uymA:
10.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 TYR A 122
PHE A 130
TYR A 136
PHE A 229
HIS A 374
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
None
None
 1.06A 5v5zA-4uymA:
50.2		 5v5zA-4uymA:
45.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AY4_A_TPFA506_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 10 TYR A 122
PHE A 130
TYR A 136
ALA A 303
ALA A 307
CYH A 463
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
HEM  A 580 (-2.3A)
 0.80A 6ay4A-4uymA:
43.8		 6ay4A-4uymA:
35.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AY6_A_VORA501_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		6 / 9 TYR A 122
PHE A 130
TYR A 136
ALA A 303
ALA A 307
CYH A 463
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
HEM  A 580 (-2.3A)
 0.81A 6ay6A-4uymA:
43.9		 6ay6A-4uymA:
35.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 PHE A 130
TYR A 136
ALA A 303
ALA A 307
LEU A 503
 VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
VOR  A 590 (-3.5A)
 0.93A 6aybA-4uymA:
39.1		 6aybA-4uymA:
35.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 TYR A 122
PHE A 130
TYR A 136
ALA A 303
ALA A 307
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
 0.71A 6aybA-4uymA:
39.1		 6aybA-4uymA:
35.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 TYR A 122
PHE A 130
TYR A 136
ALA A 303
ALA A 307
 VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
HEM  A 580 (-4.6A)
VOR  A 590 ( 4.4A)
VOR  A 590 ( 4.0A)
 0.69A 6aycA-4uymA:
44.1		 6aycA-4uymA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 8 LEU A 473
TYR A 470
GLU A 466
THR A 315
 None
None
None
HEM  A 580 ( 4.2A)
 1.18A 6c71B-4uymA:
undetectable		 6c71B-4uymA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		5 / 12 GLY A  69
TYR A 122
PHE A 130
PHE A 229
HIS A 374
 None
VOR  A 590 (-3.8A)
VOR  A 590 (-4.6A)
None
None
 1.11A 6e8qA-4uymA:
51.9		 6e8qA-4uymA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 4uym 14-ALPHA STEROL
DEMETHYLASE
(Aspergillus
fumigatus) 		4 / 6 LEU A 323
PRO A 421
HIS A 422
GLU A 332
 None
 1.05A 6pahA-4uymA:
undetectable		 6pahA-4uymA:
23.19