SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uyp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		5 / 9 VAL A 100
GLY A  14
TYR A 110
ALA A  13
GLU A 108
 None
 1.19A 1cetA-4uypA:
undetectable		 1cetA-4uypA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		4 / 4 ILE A  56
MET A  75
VAL A   4
GLY A  53
 None
 1.09A 1e06B-4uypA:
undetectable		 1e06B-4uypA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		4 / 7 PHE A  36
THR A  22
VAL A  19
ILE A  21
 None
 0.83A 1p7rA-4uypA:
undetectable		 1p7rA-4uypA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4uyp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		4 / 7 GLY B  37
PHE B  32
PRO B  33
ASP B   8
 EPE  B1076 ( 4.6A)
None
None
CA  B 201 (-2.9A)
 1.08A 2aouB-4uypB:
undetectable		 2aouB-4uypB:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		4 / 6 ILE A  31
ARG A  85
ILE A  56
PHE A  93
 None
 1.14A 2q72A-4uypA:
undetectable		 2q72A-4uypA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		5 / 12 TYR A  66
GLY A  71
ILE A 112
ASP A 136
PHE A  36
 SO4  A1147 (-4.8A)
None
None
None
None
 1.37A 2zznB-4uypA:
undetectable		 2zznB-4uypA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		4 / 8 VAL A  19
VAL A  47
PHE A  40
THR A  38
 None
 1.14A 3fhxB-4uypA:
undetectable		 3fhxB-4uypA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		4 / 6 THR A 114
ILE A  31
ASP A   5
THR A  38
 None
 0.84A 3q70A-4uypA:
undetectable		 3q70A-4uypA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		4 / 6 THR A 114
ILE A  87
ASP A   5
THR A  38
 None
 0.90A 3q70A-4uypA:
undetectable		 3q70A-4uypA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 4uyp CELLULOSOMAL
SCAFFOLDIN ANCHORING
PROTEIN C
(Acetivibrio
cellulolyticus) 		4 / 8 ILE A  31
VAL A  26
PRO A  27
VAL A 132
 None
 0.72A 4jltA-4uypA:
undetectable		 4jltA-4uypA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 4uyp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
(Acetivibrio
cellulolyticus) 		5 / 11 GLU B  35
GLY B   5
ASP B  17
ALA B  40
VAL B  13
 EPE  B1076 (-4.2A)
None
CA  B 201 (-2.2A)
None
None
 1.10A 5yk2A-4uypB:
undetectable		 5yk2A-4uypB:
9.98