SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uys'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FML_A_RTLA401_0 (RETINOL DEHYDRATASE)	4uys	FLOCCULATION PROTEIN FLO11 (Saccharomyces cerevisiae)	5 / 12	TYR A 113 TYR A 118 LEU A 93 LEU A 110 ILE A 120	None	1.38A	1fmlA-4uysA: undetectable	1fmlA-4uysA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QVU_A_PRLA196_0 (TRANSCRIPTIONAL REGULATOR QACR)	4uys	FLOCCULATION PROTEIN FLO11 (Saccharomyces cerevisiae)	4 / 6	LEU A 90 THR A 171 TYR A 154 TYR A 113	None	1.42A	1qvuA-4uysA: undetectable	1qvuA-4uysA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B9E_A_SAMA1201_0 (NOL1/NOP2/SUN DOMAIN FAMILY, MEMBER 5 ISOFORM 2)	4uys	FLOCCULATION PROTEIN FLO11 (Saccharomyces cerevisiae)	5 / 12	PRO A 193 GLY A 194 ASN A 42 ASP A 191 PHE A 126	None	1.31A	2b9eA-4uysA: undetectable	2b9eA-4uysA: 19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_D_ADND500_2 (ADENOSYLHOMOCYSTEINA SE)	4uys	FLOCCULATION PROTEIN FLO11 (Saccharomyces cerevisiae)	4 / 5	LEU A 63 GLN A 149 THR A 177 LEU A 110	None	1.25A	3ce6D-4uysA: undetectable	3ce6D-4uysA: 16.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FML_A_RTLA401_0","RETINOL DEHYDRATASE","4uys","FLOCCULATION PROTEIN FLO11","Saccharomyces cerevisiae",5,"TYR A 113;TYR A 118;LEU A  93;LEU A 110;ILE A 120","None","1.38A","1fmlA-4uysA:undetectable","1fmlA-4uysA:18.79"],["1QVU_A_PRLA196_0","TRANSCRIPTIONAL REGULATOR QACR","4uys","FLOCCULATION PROTEIN FLO11","Saccharomyces cerevisiae",4,"LEU A  90;THR A 171;TYR A 154;TYR A 113","None","1.42A","1qvuA-4uysA:undetectable","1qvuA-4uysA:19.32"],["2B9E_A_SAMA1201_0","NOL1\/NOP2\/SUN DOMAIN FAMILY, MEMBER 5 ISOFORM 2","4uys","FLOCCULATION PROTEIN FLO11","Saccharomyces cerevisiae",5,"PRO A 193;GLY A 194;ASN A  42;ASP A 191;PHE A 126","None","1.31A","2b9eA-4uysA:undetectable","2b9eA-4uysA:19.46"],["3CE6_D_ADND500_2","ADENOSYLHOMOCYSTEINASE","4uys","FLOCCULATION PROTEIN FLO11","Saccharomyces cerevisiae",4,"LEU A  63;GLN A 149;THR A 177;LEU A 110","None","1.25A","3ce6D-4uysA:undetectable","3ce6D-4uysA:16.19"]]