SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uz0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)
4uz0 NUCLEOLAR PROTEIN 3
(Homo
sapiens)
4 / 5 THR A  22
GLU A  15
THR A  11
LEU A  62
None
1.29A 1d4fC-4uz0A:
undetectable
1d4fC-4uz0A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)
4uz0 NUCLEOLAR PROTEIN 3
(Homo
sapiens)
5 / 12 LEU A  19
ALA A  80
LEU A  40
ILE A  12
LEU A  48
None
1.12A 5ljeA-4uz0A:
undetectable
5ljeA-4uz0A:
20.00