SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uzy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 8 ASN A 244
ASP A 275
LEU A 279
LEU A 274
 None
 0.82A 1e7cA-4uzyA:
2.2		 1e7cA-4uzyA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 6 SER A 227
VAL A 228
GLY A 229
GLU A 236
 None
 0.98A 1fduD-4uzyA:
undetectable		 1fduD-4uzyA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		6 / 12 SER A 423
LEU A 349
LEU A 317
ALA A 330
ILE A 357
ALA A 356
 None
FLC  A1647 (-3.9A)
None
None
None
None
 1.13A 2bxcA-4uzyA:
undetectable		 2bxcA-4uzyA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 PHE A 367
LEU A 349
GLY A 417
ILE A 424
ASP A 427
 None
FLC  A1647 (-3.9A)
None
None
None
 1.29A 2zznB-4uzyA:
undetectable		 2zznB-4uzyA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 5 GLN A 192
PHE A 193
LEU A 185
PHE A 154
 None
 1.09A 3ablC-4uzyA:
undetectable
3ablJ-4uzyA:
undetectable		 3ablC-4uzyA:
16.95
3ablJ-4uzyA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A 595
SER A 598
PHE A 600
ILE A 603
 None
 0.87A 3ko0B-4uzyA:
undetectable		 3ko0B-4uzyA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A 595
SER A 598
PHE A 600
ILE A 603
 None
 0.88A 3ko0S-4uzyA:
undetectable		 3ko0S-4uzyA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 8 GLU A 236
TYR A  55
PHE A  29
GLN A  27
 None
 1.17A 3mjrD-4uzyA:
undetectable		 3mjrD-4uzyA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 11 ILE A 585
PHE A 642
SER A 561
ILE A 559
LEU A 584
 None
 1.16A 3qg2B-4uzyA:
undetectable		 3qg2B-4uzyA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VXI_A_ASCA502_0
(DYP)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
INTRAFLAGELLAR
TRANSPORT PROTEIN
IFT52
(Chlamydomonas
reinhardtii;
Chlamydomonas
reinhardtii) 		4 / 5 ALA B 346
ASN A 314
PRO A 309
HIS A 280
 None
 1.04A 3vxiA-4uzyB:
undetectable		 3vxiA-4uzyB:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 5 ILE A 470
ILE A 500
TYR A 499
GLU A 509
 None
 1.12A 4a99D-4uzyA:
undetectable		 4a99D-4uzyA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
INTRAFLAGELLAR
TRANSPORT PROTEIN
IFT52
(Chlamydomonas
reinhardtii) 		3 / 3 SER A  90
TYR A  70
PRO B 355
 None
 0.99A 4kanB-4uzyA:
undetectable		 4kanB-4uzyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
INTRAFLAGELLAR
TRANSPORT PROTEIN
IFT52
(Chlamydomonas
reinhardtii) 		3 / 3 SER A  90
TYR A  70
PRO B 355
 None
 0.97A 4kbeB-4uzyA:
undetectable		 4kbeB-4uzyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 ILE A 470
ALA A 456
LEU A 484
VAL A 515
LEU A 511
 None
 1.00A 4km2B-4uzyA:
undetectable		 4km2B-4uzyA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		3 / 3 ASP A  82
HIS A 110
LYS A  84
 None
 0.94A 4qzuD-4uzyA:
undetectable		 4qzuD-4uzyA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 11 LEU A 453
LEU A 495
ASN A 494
ALA A 469
ILE A 470
 None
 1.17A 4x20D-4uzyA:
undetectable		 4x20D-4uzyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 5 GLN A  37
HIS A  35
ILE A  33
TYR A  57
 None
 1.21A 5dnuA-4uzyA:
undetectable		 5dnuA-4uzyA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 5 GLN A  37
HIS A  35
ILE A  33
TYR A  57
 None
 1.24A 5dnvA-4uzyA:
undetectable		 5dnvA-4uzyA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 4 ILE A 537
ILE A 541
ARG A 557
LEU A 511
 None
 1.32A 5dzkh-4uzyA:
undetectable
5dzkn-4uzyA:
undetectable
5dzkv-4uzyA:
undetectable		 5dzkh-4uzyA:
14.89
5dzkn-4uzyA:
14.89
5dzkv-4uzyA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 7 VAL A 455
TYR A 472
GLU A 447
HIS A 448
 None
 0.66A 5ecmD-4uzyA:
1.4		 5ecmD-4uzyA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
INTRAFLAGELLAR
TRANSPORT PROTEIN
IFT52
(Chlamydomonas
reinhardtii) 		4 / 5 ALA A 410
PRO A 416
GLY A 325
LEU B 343
 None
FLC  A1647 (-3.5A)
None
None
 0.92A 5eslA-4uzyA:
undetectable		 5eslA-4uzyA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA404_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 4uzy FLAGELLAR ASSOCIATED
PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 4 TYR A 425
ASN A 433
ILE A 437
GLN A 440
 None
MLI  A1648 (-4.6A)
None
None
 1.20A 5hhjA-4uzyA:
0.0		 5hhjA-4uzyA:
18.98