SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		5 / 11 ASN A 144
LEU A  55
GLU A 142
GLY A 147
ARG A 231
 GOL  A1364 (-3.6A)
None
None
GOL  A1364 ( 3.9A)
None
 1.32A 1l5rA-4v0jA:
undetectable		 1l5rA-4v0jA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		5 / 11 GLU A 143
HIS A 146
GLU A 196
ILE A 225
GLU A 229
 FE2  A 365 ( 2.4A)
FE2  A 364 (-3.3A)
FE2  A 365 (-2.0A)
None
FE2  A 364 ( 2.3A)
 0.75A 1rnrA-4v0jA:
14.6		 1rnrA-4v0jA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		5 / 12 GLU A 143
HIS A 146
GLU A 196
ILE A 225
GLU A 229
 FE2  A 365 ( 2.4A)
FE2  A 364 (-3.3A)
FE2  A 365 (-2.0A)
None
FE2  A 364 ( 2.3A)
 0.77A 1rnrB-4v0jA:
14.5		 1rnrB-4v0jA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		5 / 12 GLU A 229
HIS A 232
TYR A 236
GLU A 105
GLU A 143
 FE2  A 364 ( 2.3A)
FE2  A 365 (-3.8A)
None
FE2  A 364 (-2.0A)
FE2  A 365 ( 2.4A)
 0.90A 1rnrB-4v0jA:
14.5		 1rnrB-4v0jA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		3 / 3 GLU A 142
VAL A  58
CYH A  61
 None
 1.05A 3fbxA-4v0jA:
undetectable		 3fbxA-4v0jA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 7 VAL A 305
ILE A 190
MET A 265
ARG A 329
 None
 0.84A 3ik3A-4v0jA:
undetectable		 3ik3A-4v0jA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 7 VAL A 305
ILE A 190
MET A 265
ARG A 329
 None
 0.79A 3ik3B-4v0jA:
undetectable		 3ik3B-4v0jA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 6 VAL A 305
ILE A 190
MET A 265
ARG A 329
 None
 0.91A 3ms9A-4v0jA:
undetectable		 3ms9A-4v0jA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 6 VAL A 305
ILE A 190
MET A 265
ARG A 329
 None
 0.94A 3mssA-4v0jA:
undetectable		 3mssA-4v0jA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 6 VAL A 305
ILE A 190
MET A 265
ARG A 329
 None
 0.96A 3mssC-4v0jA:
undetectable		 3mssC-4v0jA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 5 GLN A 195
THR A 192
GLU A 143
THR A 140
 None
None
FE2  A 365 ( 2.4A)
None
 1.46A 3n58A-4v0jA:
undetectable		 3n58A-4v0jA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 5 VAL A 305
ILE A 190
MET A 265
ARG A 329
 None
 1.04A 3oezA-4v0jA:
undetectable		 3oezA-4v0jA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 5 VAL A 305
ILE A 190
MET A 265
ARG A 329
 None
 0.79A 3pyyB-4v0jA:
undetectable		 3pyyB-4v0jA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 6 THR A 110
ILE A 263
TYR A 191
THR A 113
 None
 1.11A 3q70A-4v0jA:
undetectable		 3q70A-4v0jA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		5 / 11 SER A 264
ALA A 107
GLU A 196
THR A 181
GLY A 188
 None
None
FE2  A 365 (-2.0A)
None
None
 1.44A 4zjoD-4v0jA:
undetectable		 4zjoD-4v0jA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		5 / 9 ALA A 254
VAL A 327
ALA A 323
VAL A 310
GLY A 320
 None
 1.20A 6bklA-4v0jA:
undetectable
6bklB-4v0jA:
undetectable
6bklC-4v0jA:
undetectable
6bklD-4v0jA:
undetectable		 6bklA-4v0jA:
6.69
6bklB-4v0jA:
6.69
6bklC-4v0jA:
6.69
6bklD-4v0jA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 4v0j ACYL-[ACYL-CARRIER-P
ROTEIN] DESATURASE,
CHLOROPLASTIC
(Ricinus
communis) 		4 / 6 ILE A 190
LEU A 304
VAL A 240
SER A 193
 None
 1.28A 6f6jA-4v0jA:
undetectable		 6f6jA-4v0jA:
undetectable