SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v0p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 4v0p MELANOMA-ASSOCIATED
ANTIGEN 3
(Homo
sapiens) 		5 / 5 LEU A 256
LEU A 225
ILE A 221
ILE A 208
ALA A 207
 None
 0.93A 2i2zA-4v0pA:
undetectable		 2i2zA-4v0pA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 4v0p MELANOMA-ASSOCIATED
ANTIGEN 3
(Homo
sapiens) 		4 / 4 LEU A 256
ILE A 221
ILE A 208
ALA A 207
 None
 0.80A 2i30A-4v0pA:
undetectable		 2i30A-4v0pA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4v0p MELANOMA-ASSOCIATED
ANTIGEN 3
(Homo
sapiens) 		4 / 8 ALA A 199
TYR A 124
GLY A 163
ILE A 164
 None
 0.87A 2zm9A-4v0pA:
undetectable		 2zm9A-4v0pA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4v0p MELANOMA-ASSOCIATED
ANTIGEN 3
(Homo
sapiens) 		5 / 12 LEU A 202
ALA A 277
LEU A 256
ALA A 210
ILE A 221
 None
 1.01A 4x20B-4v0pA:
undetectable		 4x20B-4v0pA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 4v0p MELANOMA-ASSOCIATED
ANTIGEN 3
(Homo
sapiens) 		5 / 12 LEU A 202
ALA A 277
LEU A 256
ALA A 210
ILE A 221
 None
 1.01A 5xiwB-4v0pA:
undetectable		 5xiwB-4v0pA:
20.00