SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v10'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4v10 MYOMESIN-1
(Mus
musculus) 		4 / 7 ILE A 168
SER A 144
TYR A 205
CYH A 190
 None
 1.21A 2xz5D-4v10A:
undetectable
2xz5E-4v10A:
undetectable		 2xz5D-4v10A:
19.42
2xz5E-4v10A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4v10 MYOMESIN-1
(Mus
musculus) 		4 / 7 ILE A 162
ARG A 213
VAL A 169
TRP A 170
 None
 1.29A 4f4dA-4v10A:
undetectable		 4f4dA-4v10A:
24.11