SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 4v17 CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		5 / 11 LEU A 551
VAL A 457
ILE A 463
ILE A 578
PHE A 486
 None
 1.27A 1gx9A-4v17A:
undetectable		 1gx9A-4v17A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 4v17 CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		3 / 3 GLU A 521
TYR A 495
SER A 489
 None
 0.99A 4at0A-4v17A:
undetectable		 4at0A-4v17A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 4v17 CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		3 / 3 GLU A 445
GLY A 444
SER A 580
 None
 0.71A 4b53B-4v17A:
undetectable		 4b53B-4v17A:
20.73